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Internalized Stigma in Patients With Bipolar Disorder or Schizophrenia (ESTINT)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2012 by University of Sao Paulo.
Recruitment status was  Recruiting
Sponsor:
Information provided by (Responsible Party):
Ricardo Alberto Moreno, M.D., Ph.D., University of Sao Paulo
ClinicalTrials.gov Identifier:
NCT01664884
First received: August 10, 2012
Last updated: August 15, 2012
Last verified: August 2012
  Purpose

The aim of this study is to explore the levels of internalized stigma in a sample of young patients with bipolar disorder or schizophrenia.


Condition
Stigma

Study Type: Observational
Study Design: Observational Model: Ecologic or Community
Time Perspective: Cross-Sectional
Official Title: Internalized Stigma in a Sample of Young Adults With Bipolar Disorder or Schizophrenia.

Resource links provided by NLM:


Further study details as provided by University of Sao Paulo:

Estimated Enrollment: 120
Study Start Date: June 2012
Estimated Study Completion Date: January 2013
Estimated Primary Completion Date: January 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts
Bipolar Disorder Patients
Bipolar Disorder Patients, with age between 18 to 40 years old, at euthymic phase.
Schizophrenia Patients
Schizophrenia Patients, with age between 18 to 40 years old, with minimum or none positive symptoms.

Detailed Description:

The stigma is considered by patients, government organizations and health professionals a key point in mental illness (Griffiths et al, 2006). The related literature has focused on individuals with schizophrenia although there are indications that stigma act negatively in patients with bipolar disorder; this, in turn, is described in a few studies, always with heterogeneous samples, chronic and symptomatic patients (Perlick et al, 2001). It is also known that there is a significant association between affective symptoms and the presence of stigma, (Vázquez et al, 2010).

There are reports of higher levels of public stigma towards people with schizophrenia, compared to patients with bipolar disorder or unipolar depression, however there are no studies available on internalized stigma in such samples, especially in remitted patients . Since schizophrenia coexists with significant impairment of insight, such individuals may exhibit more difficulty internalizing the external bias and stereotypes. On the other hand, patients with bipolar disorder - despite being less discriminated by the public in relation to schizophrenia - probably have a high potential for self-stigma and its fearsome consequences, justified by higher levels of insight.

The investigators would like to examine whether the lower impairment of insight in young bipolar patients(in relation to young people with schizophrenia) could be accompanied by an increase in internalized stigma in this sample. It´s an observational, cross-sectional study with no intervention.

Hypothesis: the internalized stigma in young adults with bipolar disorder is identical to that of young patients with schizophrenia.

  Eligibility

Ages Eligible for Study:   18 Years to 40 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

The group will consist of patients from the Institute of Psychiatry, Hospital das Clinicas, Faculty of Medicine, University of São Paulo (HCFMUSP) diagnosed by DSM-IV-TR bipolar disorder (in remission) or schizophrenia (absence of positive symptoms).

Criteria

Inclusion Criteria:

  • Diagnosis of bipolar disorder and schizophrenia according to DSM-IV-TR, presenting in euthymia (bipolar disorder) or without positive symptoms (schizophrenia), based on clinical assessment and confirmed by structured clinical interview SCID-P
  • Age between 18 and 40 years
  • Literate and able to understand the tasks required.
  • Residents of Greater Sao Paulo.
  • Patients and / or legal representatives must understand the nature of the study and sign an informed consent.

Exclusion Criteria:

  • Patients with Schizoaffective Disorder or Mental Retardation.
  • Unstable serious diseases including kidney disease, gastroenterology, respiratory, cardiovascular, endocrine, neurological, immunological or haematological.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01664884

Contacts
Contact: Luis Felipe Oliveira Costa, M.D. +551198053654 luis@costa.med.br

Locations
Brazil
PROGRUDA-Institute of Psychiatry- HCFMUSP Recruiting
Sao Paulo, SP, Brazil
Contact: Nayara Rodrigues, Secretary    +551126616648    gruda@hcnet.usp.br   
Sub-Investigator: Luis Felipe de Oliveira Costa, MD         
Sponsors and Collaborators
University of Sao Paulo
Investigators
Study Director: Ricardo Alberto Moreno, MD PhD University of Sao Paulo
  More Information

No publications provided

Responsible Party: Ricardo Alberto Moreno, M.D., Ph.D., Ricardo Alberto Moreno, University of Sao Paulo
ClinicalTrials.gov Identifier: NCT01664884     History of Changes
Other Study ID Numbers: ESTINT
Study First Received: August 10, 2012
Last Updated: August 15, 2012
Health Authority: Brazil: National Committee of Ethics in Research

Keywords provided by University of Sao Paulo:
INTERNALIZED STIGMA
INSIGHT
SOCIAL ADEQUACY
BIPOLAR DISORDER
SCHIZOPHRENIA

Additional relevant MeSH terms:
Bipolar Disorder
Schizophrenia
Affective Disorders, Psychotic
Mental Disorders
Mood Disorders
Schizophrenia and Disorders with Psychotic Features

ClinicalTrials.gov processed this record on November 20, 2014