Optical Biometry and Spherical Aberration in Ametropic and Emmetropic Eyes
Aberrations play a significant role in the visual process and can be divided in lower-order and higher-order aberrations. The former can be measured using the commercially available IOL Master (Carl Zeiss Meditec AG, Germany) and have profound influence on visual acuity. Higher-order aberrations do not significantly influence visual acuity but affect the quality of vision and can cause halos, double vision, and night vision disturbances.
Background Cataract surgery has become a routine procedure in the developed countries. During this surgery, a foldable intraocular lens is usually inserted into the capsular bag. However, these lenses do not account for individual optical biometry data or aberrations. Therefore, it is important to provide data for ametropic and emmetropic eyes as this information might improve future intraocular lens design and lead to individually adapted lenses for yielding optimal visual acuity and quality results.
The aim of the present study is to clarify the correlation between refractive errors/axial eye length and spherical aberrations of the cornea.
Axial Length, Eye
Corneal Wavefront Aberration
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Optical Biometry and Spherical Aberration in Ametropic and Emmetropic Eyes|
- Axial eye length [ Time Frame: 1 day ] [ Designated as safety issue: No ]
- Refractive error [ Time Frame: 1 day ] [ Designated as safety issue: No ]
- Corneal radius [ Time Frame: 1 day ] [ Designated as safety issue: No ]
- Pupil diameter [ Time Frame: 1 day ] [ Designated as safety issue: No ]
- Anterior chamber depth [ Time Frame: 1 day ] [ Designated as safety issue: No ]
- Anterior corneal topography [ Time Frame: 1 day ] [ Designated as safety issue: No ]
- Corneal thickness map [ Time Frame: 1 day ] [ Designated as safety issue: No ]
|Study Start Date:||August 2012|
|Study Completion Date:||May 2013|
|Primary Completion Date:||May 2013 (Final data collection date for primary outcome measure)|
40 subjects with high grarde myopia ranging from -10 diopters to -4.01 diopters
40 subjects with moderate myopia ranging from -4 diopters to -1.01 diopter
40 subjects with emmetropia, -1 diopter to +1 diopter
40 subjects with hyperopia, +1.01 diopter and more