Effect of Erythromycin Before Endoscopy of Patients With Subtotal Gastrectomy (STG), High Risk of Gastric Stasis
Erythromycin has a prokinetic effect through Motilin receptor. It evokes migrating motor complex with longer and stronger contraction.
In patients with upper gastrointestinal bleeding, It has been shown that erythromycin could clear the stomach of blood, so visual examination could be improved.
Frequent food stasis is encounted when we examine patients with subtotal gastrectomy. It is postulated that erythromycin reduce food stasis and help to improve endoscopy in these cases.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Prevention
|Official Title:||Effect of Erythromycin Before Endoscopy of Patients With Subtotal Gastrectomy (STG), High Risk of Gastric Stasis : Randomized and Prospective Study|
- degree of food stasis [ Time Frame: when endoscopy is performed. ] [ Designated as safety issue: No ]ref> Gastric Cancer (2002) 5: 83-89
|Study Start Date:||April 2012|
|Study Completion Date:||October 2012|
|Primary Completion Date:||October 2012 (Final data collection date for primary outcome measure)|
125mg in normal saline single use infusion for 5 min.
|No Intervention: saline|
|Korea, Republic of|
|Seoul St. Mary hospital|
|Seoul, Korea, Republic of|
|Principal Investigator:||Myung-Gyu Choi, M.D.||Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea|