Diaphragmatic Function in Stroke Patients.
- This study attempts to elucidate whether stroke patients with dysphagia have reduced diaphragm movement during voluntary coughing, and also during deep inspiration and expiration than stroke patients without dysphagia.
- This study will also compare various spirometric measurements with the diaphragmatic motions.
|Study Design:||Time Perspective: Cross-Sectional|
|Official Title:||Diaphragm Function Evaluation in Stroke Patients During Voluntary Cough Using Sonography|
- Diaphragm movement during coughing [ Time Frame: 1 day ] [ Designated as safety issue: No ]Diaphragm movement during voluntary coughing will be recorded by musculoskeletal sonogrpahy
- Maximal inspiratory and expiratory pressure [ Time Frame: 1 day ] [ Designated as safety issue: No ]respiratory pressure meter would be used to measure inspiratory and expiratory strength
- Pulmonary Function test [ Time Frame: 1 day ] [ Designated as safety issue: No ]FVC, FEV1, FEF 25-75%, FVC/FEV1 ( % ), Peak cough flow
- Motricity index [ Time Frame: Baseline ] [ Designated as safety issue: No ]
- Canadian Neurological Stroke Scale [ Time Frame: Baseline ] [ Designated as safety issue: No ]
- Diaphragm movement during inspiration [ Time Frame: 1 day ] [ Designated as safety issue: No ]Diaphragm movement will be recorded after deep inspiration
- Diaphragm movement during expiration [ Time Frame: 1 day ] [ Designated as safety issue: No ]Diaphragm movement during expiration will be recorded
|Study Start Date:||June 2012|
|Study Completion Date:||June 2013|
|Primary Completion Date:||June 2013 (Final data collection date for primary outcome measure)|
Stroke patients with dysphagia
Stroke patients with confirmed evidence of aspiration and severe dysphagia tha would require modified diet or nasogastric tube feeding
Stroke patients without dysphagia
Stroke patients but with no gross evidence of dysphagia or with mild dysphagia with a Penetration aspiration scale of less than 4
healthy volunteer group
healthy volunteers with no prior history of dysphagia or stroke and who are not included in the exclusion criteria
Stroke is a debilitating condition that can impair multiple functions, including swallowing. Stroke patients with dysphagia, are known to have reduced cough due to multiple mechanisms and this can impair their expectorate function. This can lead to accumulation of sputum and mucoid, ultimately resulting in aspiration pneumonia. Stroke patients, especially those with dysphagia, are also known to have expiratory muscle weakness and weak cough than healthy controls. Stroke patients are also known to have reduced diaphragm movement than healthy subjects. Sonography is a useful tool that can easily and reliability measure diaphragm movement. Whether stroke patients with dysphagia have reduced diaphragm movement than those without dysphagia and whether this affects voluntary cough have not been reported yet.
This study attempts to evaluate diaphragm movements during voluntary cough in stroke patients with dysphagia and determine whether this reduced diaphragm movement correlates to their peak flow meters during voluntary cough.
|Korea, Republic of|
|Bucheon St Mary's Hospital, Catholic University of Korea|
|Bucheon, Gyenoggido, Korea, Republic of, 420-717|
|Principal Investigator:||Sun Im, MD, PhD||Department of Rehabilitation Medicine, Bucheon St Mary's Hospital, Catholic University of Korea, College of medicine|