NT-proBNP as a Tool for the Detection of Acute Pulmonary Artery Embolism (APE)
In patients with suspected APE (Acute Pulmonary Embolism) referred to the intensive care unit (ICU)after major surgery, serum NT-proBNP (N-terminal proBNP), Troponin-I and D-dimers were measured according to the standard hospital protocol. To definitively confirm or exclude APE, all patients underwent an angiographic CT-scan of the thorax.
Pulmonary Embolism Without Mention of Acute Cor Pulmonale
|Study Design:||Observational Model: Case Control
Time Perspective: Retrospective
|Official Title:||NT-proBNP: a Useful Tool for the Detection of Acute Pulmonary Artery Embolism in Post-surgical Patients|
- Acute pulmonary embolism: CT-proof yes vs. no [ Time Frame: 1 hour after onset of clinical symptoms ] [ Designated as safety issue: No ]
|Study Start Date:||November 2008|
|Study Completion Date:||December 2011|
|Primary Completion Date:||December 2011 (Final data collection date for primary outcome measure)|
Post-surgical patients with clinically suspected acute pulmonary embolism
In patients with suspected APE referred to the intensive care unit after major surgery, serum NT-proBNP, Troponin-I and D-dimers were measured according to the standard hospital protocol. Blood samples were obtained within one hour after the onset of clinical symptoms.
Definitive confirmation or exclusion of APE was performed with an angiographic CT-scan of the thorax.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01633671
|University of Ulm, Michelsberg anaesthesiologic ICU|
|Ulm, Baden-Wuerttemberg, Germany, 89075|
|Study Chair:||Claus M Muth, MD||Dept. of Anesthesiology, Div. of Emergency medicine, University hospital Ulm, 89075 Ulm, Germany|
|Principal Investigator:||Bernd E Winkler, MD||Dept. of Anesthesiology, University hospital Ulm, 89075 Ulm, Germany|