Autoantibodies Against Specific Cytokines in Adults With Severe Mycobacterial Infection

This study is currently recruiting participants.
Verified June 2012 by China Medical University Hospital
Information provided by (Responsible Party):
China Medical University Hospital Identifier:
First received: June 24, 2012
Last updated: June 26, 2012
Last verified: June 2012

In adult, the prevalence of mycobacterial infections is increased with age is largely unknown. IFN-gamma-IL-12/23 axis or NF-kappaB pathways might also plays crucial roles in adult against mycobacteria. Based on this hypothesis, the investigators had applied a functional assay to these pathways in patients with mycobacterial infection.

Mycobacterium Infection

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective

Resource links provided by NLM:

Further study details as provided by China Medical University Hospital:

Estimated Enrollment: 100
Study Start Date: January 2011
Estimated Study Completion Date: December 2014
Patients with mycobacterial infection


Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Pateitns with Mycobacterium, Particular to the non Tuberculosis mycobacterium infection, in Taiwan


Inclusion Criteria:

  • Patients with mycobacterial infection

Exclusion Criteria:

  • Malignancy
  • Severe autoimmune
  • HIV infection
  Contacts and Locations
Please refer to this study by its identifier: NCT01628744

Contact: Cheng-?Lung KU, Ph.D (886) (0)3 211-8800 ext 3496

Graduate Institute of Clinical Medical Science, China Medical University Recruiting
Taichung, Taiwan
Principal Investigator: Chih Y. Chi, M.D,         
Sponsors and Collaborators
China Medical University Hospital
Principal Investigator: Cheng-Lung KU, Ph.D Graduate Institute of clinical Medical Science, China Medical Univerity, Taiwan
  More Information

No publications provided

Responsible Party: China Medical University Hospital Identifier: NCT01628744     History of Changes
Other Study ID Numbers: DMR-99-IRB-075-1
Study First Received: June 24, 2012
Last Updated: June 26, 2012
Health Authority: Taiwan: Department of Health

Additional relevant MeSH terms:
Mycobacterium Infections
Actinomycetales Infections
Gram-Positive Bacterial Infections
Bacterial Infections processed this record on April 17, 2014