Evaluation of One-day Polyethylene Glycol Powder Solution for Colonoscopy in Children

• electrolyte disturbances [ Time Frame: at the time of colonoscopy ] [ Designated as safety issue: Yes ]
  the proportion of patients with clinically significant serum electrolyte abnormalities at the time of colonoscopy
  
  
• PEG-P preparation tolerance [ Time Frame: at the time of colonoscopy ] [ Designated as safety issue: No ]
  Responses to a questionnaire regarding the tolerance of the PEG-P prep will be recorded
  
  

• Colonoscopy preparation efficacy [ Time Frame: at the time of colonoscopy ] [ Designated as safety issue: No ]
  To assess the proportion of patients that have excellent or good quality preparation as scored by a validated residual stool survey called the Aronchick scale
  
  
• Effective communication [ Time Frame: at the time of colonoscopy ] [ Designated as safety issue: No ]
  Effectiveness of communication strategy about the prep and availability of staff to address questions reported by parents will be summarized
  
  

Design is prospective, descriptive observational study involving a single clinical encounter in the Endoscopy suite at CHOP Main at the time of colonoscopy. Patients prescribed the standard of care dosage for PEG-P by their primary gastroenterologist are considered for this study. Study procedures include collection of data from patients that are prescribed the PEG-P dose. In order to evaluate the safety, tolerability, and adherence to PEG-P bowel preparation, data collections include the following: review of medical records, tracking of communication from subjects/parents, blood draw, questionnaire and quality of prep will be assessed. Questionnaire results will be obtained at the initial and only visit. Patients will be given a questionnaire prior to colonoscopy to rate symptoms, ease of preparation and to rate the effectiveness of communication about the preparation. On the day of colonoscopy, prior to the procedure, patients will have an IV placed per standard procedure. At the time of IV placement, a basic metabolic panel and serum magnesium and phosphorus levels will be drawn through the IV for assessment of electrolyte abnormalities. Serum glucose will be captured from medical records as this is collected with standard of care. Patient/parents will grade the preparation tolerance filling out a questionnaire prior to colonoscopy. During colonoscopy, the endoscopist will grade the quality of preparation on a validated residual stool survey (Aronchick scale).