Stress Echocardiography Versus Coronary Angiography for Left Main Stenosis Detection (ESTRIE-TC)
This study is currently recruiting participants.
Verified June 2012 by Universitaire de Sherbrooke
Sponsor:
Universitaire de Sherbrooke
Information provided by (Responsible Party):
Paul Farand, Universitaire de Sherbrooke
ClinicalTrials.gov Identifier:
NCT01620320
First received: July 16, 2010
Last updated: June 14, 2012
Last verified: June 2012
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Purpose
Left main stenosis use to be treated by bypass but with the improvement of angioplasty techniques, an increasing number of patients are submit to left main coronary angioplasty. Consequences of left main intra stent stenosis can be disastrous yet, for the moment, no precise recommendation concerning the follow up of these patients exist. The investigators ought to determine if stress echocardiography can predict left main intra stent stenosis as well (non inferiorly)as control angiography that use to be done.
| Condition | Intervention |
|---|---|
|
Left Main Coronary Artery Disease Stenosis |
Other: Stress echocardiography |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Prospective |
| Official Title: | Évaluation de l'Echographie de Stress Par Comparaison à la Coronarographie Comme Outil Non Invasif de détection de la resténose Intra endoprothèse du Tronc Commun |
Resource links provided by NLM:
Further study details as provided by Universitaire de Sherbrooke:
Primary Outcome Measures:
- Correlation between stress echocardiography results for the detection of left main prosthesis stenosis with coronary angiogram results. [ Time Frame: 9 to 12 months after left main angioplasty ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 50 |
| Study Start Date: | July 2010 |
| Estimated Study Completion Date: | July 2013 |
| Estimated Primary Completion Date: | July 2012 (Final data collection date for primary outcome measure) |
| Groups/Cohorts | Assigned Interventions |
|---|---|
|
Stress echography
Nine to twelve months after their left main angioplasty, patients will go through a stress echo and then the usual control angiography (done routinely in most patient in our center). Patients will act as their own control.
|
Other: Stress echocardiography
Patients able to exercise will have a treadmill test + echography; the others will have a dobutamine echography.
Other Names:
|
Detailed Description:
All patients of the study will pass coronary angiogram and stress echocardiography (treadmill of dobutamine).
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Study Population
Patients presenting to teaching hospital or stent from community hospitals to teaching hospital and having left main angioplasty
Criteria
Inclusion Criteria:
- patients over 18 years old able to give consent and having had left main angioplasty.
Exclusion Criteria:
- Bypass on the left anterior descending coronary artery or left circumflex (" protected left main ")
- Treating physician judge that angiography need to be done straightaway
- Follow up elsewhere than the CHUS
- Patient refusal
- Pregnant women
- Stress echo contraindication(Severe high blood pressure or malignant arrhythmia)or condition that limits interpretation (Left bundle branch block or pacemaker rhythm)
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01620320
Contacts
| Contact: Paul Farand, Cardiologue | (819) 346-1110 ext 9093 (pagette) | paul.farand@usherbrooke.ca |
| Contact: Marie-Eve Pelletier, Residente | (819) 346-1110 ext 2107 (pagette) | pelletiermarieeve@hotmail.com |
Locations
| Canada, Quebec | |
| Centre Hospitalier Universitaire de Sherbrooke, departement de cardiologie | Recruiting |
| Sherbrooke, Quebec, Canada, J1H 5N4 | |
| Contact: Paul Farand, Cardiologue (819) 346-1110 ext 9093 (pagette) paul.farand@usherbrooke.ca | |
| Contact: Marie-Eve Pelletier, Residente (819) 346-1110 ext 2107 (pagette) pelletiermarieeve@hotmail.com | |
| Principal Investigator: Paul Farand, Cardiologue | |
Sponsors and Collaborators
Universitaire de Sherbrooke
Investigators
| Principal Investigator: | Paul Farand, Cardiologue | Centre Hospitalier Universitaire de Sherbrooke |
More Information
No publications provided
| Responsible Party: | Paul Farand, Doctor, Universitaire de Sherbrooke |
| ClinicalTrials.gov Identifier: | NCT01620320 History of Changes |
| Other Study ID Numbers: | projet #10-011 |
| Study First Received: | July 16, 2010 |
| Last Updated: | June 14, 2012 |
| Health Authority: | Canada: Health Canada |
Keywords provided by Universitaire de Sherbrooke:
|
Left main coronary artery Coronary artery disease Stress echography Intrastent stenosis |
Additional relevant MeSH terms:
|
Constriction, Pathologic Coronary Artery Disease Myocardial Ischemia Coronary Disease Pathological Conditions, Anatomical Heart Diseases Cardiovascular Diseases Arteriosclerosis Arterial Occlusive Diseases Vascular Diseases Dobutamine Cardiotonic Agents Cardiovascular Agents |
Therapeutic Uses Pharmacologic Actions Sympathomimetics Autonomic Agents Peripheral Nervous System Agents Physiological Effects of Drugs Adrenergic beta-1 Receptor Agonists Adrenergic beta-Agonists Adrenergic Agonists Adrenergic Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Protective Agents |
ClinicalTrials.gov processed this record on May 19, 2013