Clinical Profiles and Outcomes of Acute Aortic Dissection in the Chinese Patients (CPOAADCP)

This study has been completed.
Sponsor:
Collaborator:
Changhai Hospital
Information provided by (Responsible Party):
Yang Li, MD, Xijing Hospital
ClinicalTrials.gov Identifier:
NCT01606943
First received: March 1, 2012
Last updated: May 25, 2012
Last verified: May 2012
  Purpose

Clinical profiles and outcomes of patients with acute aortic dissection have not yet been evaluated in China. The aim of this study is to establish clinical registry of acute aortic dissection in China and to analyze clinical features, managements and outcomes of Chinese patients with acute aortic dissection.


Condition
Aorta Thoracic Ascending Dissection
Dissection of Descending Aorta

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: The Study of The Chinese Registry of Acute Aortic Dissection and Clinical Study of Acute Aortic Dissection in Chinese Patients

Further study details as provided by Xijing Hospital:

Enrollment: 2000
Study Start Date: January 2009
Study Completion Date: February 2012
Primary Completion Date: February 2012 (Final data collection date for primary outcome measure)
Detailed Description:

In 1996, the Internation Registry of Acute Aortic Dissection(IRAD) was established to improve clinical diagnosis and treatment of acute aortic dissection. However, most patients from the IRAD are Caucasian. These data were not sufficient to reflect clinical profiles and outcomes of Chinese patients with acute aortic dissection. In China, little is known about clinical features, managements and outcomes of acute aortic dissection involving a large number of patients. The investigators established clinical multicenter registry of acute aortic dissection. Between January 2009 and February 2012, about 2000 were enrolled in the Chinese registry of acute aortic dissection(CRAD) database. The aim of this study is to analyze clinical profiles and outcomes of Chinese patients with acute aortic dissection.

  Eligibility

Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Chinese population suffering acute aortic dissection

Criteria

Inclusion Criteria:

  • Stanford type A dissection
  • Stanford type B dissection
  • Retrograde Stanford Type B dissection
  • Unclassified dissection with primary tear located in the aortic dissection

Exclusion Criteria:

  • Aortic aneurysm
  • Active infection or active vasculitides
  • Myocardial infarction or Cerebral accident within 2 months
  • Unwillingness to cooperate wiht study procedures or follow-up visits
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01606943

Locations
China, Shaanxi
Xijing Hospital
Xi'an, Shaanxi, China, 710032
Sponsors and Collaborators
Xijing Hospital
Changhai Hospital
Investigators
Study Director: Dihua Yi, MD Xijing Hospital
Principal Investigator: Yang Li, MD General Hospital of Beijing Military Area command of Chinese PLA
Principal Investigator: Wenxun Duan, MD Xijing Hospital
  More Information

No publications provided

Responsible Party: Yang Li, MD, Principal Investigator, Xijing Hospital
ClinicalTrials.gov Identifier: NCT01606943     History of Changes
Other Study ID Numbers: XJ201202, CRAD2011
Study First Received: March 1, 2012
Last Updated: May 25, 2012
Health Authority: China: Food and Drug Administration

Keywords provided by Xijing Hospital:
Aortic dissection
Risk factor
Feature
Management
Outcome

ClinicalTrials.gov processed this record on August 20, 2014