Trial record 13 of 52 for:    child [AGE-GROUP] "drug abuse" | Open Studies

Prevention and Reduction of Alcohol and Drug Problems in a Clinical Psychiatric Youth Population

This study is currently recruiting participants.
Verified July 2012 by St. Justine's Hospital
Sponsor:
Information provided by (Responsible Party):
Eveline Perrier-Ménard, St. Justine's Hospital
ClinicalTrials.gov Identifier:
NCT01595568
First received: May 3, 2012
Last updated: July 18, 2012
Last verified: July 2012
  Purpose

In adolescents, mental health problems are frequently associated with substance misuse, even considered a risk factor for alcohol abuse and dependence. This dual diagnosis tends to complicate the patient's treatment and prognosis by increasing, among others, substance use problems, reckless behaviours, relationships and school problems and suicidal thoughts. It is therefore critical to invest time and effort into developing an efficient approach to prevent and reduce substance use problems and offer these children a more global and optimal treatment.

A brief personality-targeted intervention was developed with students of Canadian and English high schools based on four personality factors known to be implicated in the vulnerability to adolescent alcohol misuse (Impulsivity, Anxiety Sensitivity, Negative Thinking and Sensation Seeking) (Conrod et al., 2006,2008, O'Leary-Barrett 2010).

By helping the adolescents to develop better adaptive behaviours, this cognitive-behavioural intervention proved to reduce binge drinking, quantity and frequency of use and substance use problems (Conrod et al., 2006,2011).

The purpose of this study is to assess the impact of this intervention if combined to a regular treatment in a youth psychiatric population.

60 patients aged 14-17 years of a Child and Adolescent psychiatric department will be screened for personality risk with self-report assessments including the Substance Use Risk Profile Scale. Participants will be randomly assigned to a personality matched cognitive-behavioural intervention or a no-intervention control.

The main outcome measures of this study are alcohol and illicit drug outcomes. Secondary measures include mental health symptoms.


Condition Intervention
Alcohol Abuse
Drug Abuse
Mood Disorder
Anxiety Disorder
Conduct Disorder
Behavioral: Personality-targeted interventions

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Factorial Assignment
Masking: Open Label
Primary Purpose: Prevention

Resource links provided by NLM:


Further study details as provided by St. Justine's Hospital:

Primary Outcome Measures:
  • Change in Binge drinking frequency [ Time Frame: Baseline - 4months ] [ Designated as safety issue: No ]
  • Change in Drinking frequency [ Time Frame: Baseline - 4 months ] [ Designated as safety issue: No ]
  • Change in Drinking quantity [ Time Frame: Baseline - 4 months ] [ Designated as safety issue: No ]
  • Change in Drinking problems [ Time Frame: Baseline - 4 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Change in Emotional and behavioural problems [ Time Frame: Baseline - 4 months ] [ Designated as safety issue: No ]
    Psychiatric symptoms (depression, panic anxiety, antisocial behaviours), coping skills, motives for drinking, assessed using the Strengths and Difficulties Questionnaire, the Drinking Motives Questionnaire and the Brief Symptom Inventory.


Estimated Enrollment: 60
Study Start Date: February 2012
Estimated Primary Completion Date: July 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Learning to cope with your impulsivity
Cognitive-behavioural intervention targeting impulsive personality
Behavioral: Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained therapist and co-facilitator
Other Names:
  • Preventure
  • Adventure
Experimental: Learning to cope with your sensation seeking
Cognitive behavioural intervention designed to help sensation seeking youth manage their need for stimulation and excitement.
Behavioral: Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained therapist and co-facilitator
Other Names:
  • Preventure
  • Adventure
Experimental: Learning to cope with your anxiety sensitivity
Cognitive behavioural intervention teaching anxiety sensitive youth to manager their sensitivity to threat and anxiety.
Behavioral: Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained therapist and co-facilitator
Other Names:
  • Preventure
  • Adventure
Experimental: Learning to manage your negative thinking
Cognitive behavioural intervention targeting pessimistic and negative thinking in hopeless youth
Behavioral: Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained therapist and co-facilitator
Other Names:
  • Preventure
  • Adventure

  Eligibility

Ages Eligible for Study:   14 Years to 17 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Motive for psychiatric consultation
  • Able to provide consent from parent/guardian for participation in the study
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01595568

Contacts
Contact: Eveline Perrier-Ménard, MD 514-345-4931 ext 4050 eveline.perrier-menard@umontreal.ca

Locations
Canada, Quebec
CHU Ste-Justine Recruiting
Montréal, Quebec, Canada, H3T 1C5
Contact       eveline.perrier-menard@umontreal.ca   
Sponsors and Collaborators
St. Justine's Hospital
  More Information

No publications provided

Responsible Party: Eveline Perrier-Ménard, MD, Master student, St. Justine's Hospital
ClinicalTrials.gov Identifier: NCT01595568     History of Changes
Other Study ID Numbers: CER CHU Ste-Justine 3435
Study First Received: May 3, 2012
Last Updated: July 18, 2012
Health Authority: Canada: Health Canada

Keywords provided by St. Justine's Hospital:
Adolescents
Dual Diagnosis
Mental Disorders
Substance Use Problems
Prevention

Additional relevant MeSH terms:
Anxiety Disorders
Substance-Related Disorders
Alcoholism
Conduct Disorder
Mood Disorders
Mental Disorders
Alcohol-Related Disorders
Attention Deficit and Disruptive Behavior Disorders
Mental Disorders Diagnosed in Childhood

ClinicalTrials.gov processed this record on April 15, 2014