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Improving Depression Care for Elders: Coordinating Center (IMPACT)

This study has been completed.
Sponsor:
Collaborators:
John A. Hartford Foundation
California HealthCare Foundation
Hogg Foundation
Robert Wood Johnson Foundation
Information provided by (Responsible Party):
Jurgen Unutzer, MD, MPH, University of Washington
ClinicalTrials.gov Identifier:
NCT01561105
First received: March 20, 2012
Last updated: March 26, 2012
Last verified: March 2012
History of Changes
  Purpose

Purpose: To determine the effectiveness of the Improving Mood-Promoting Access to Collaborative Treatment(IMPACT) collaborative care management program for late-life depression.


Condition Intervention
Major Depression
Dysthymic Disorder
Both Major Depression and Dysthymic Disorder
 Other: IMPACT

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: This Was a Five-year Seven-site Trial to Study the Cost-effectiveness of a Population Based Disease Management Program for Late Life Depression in Primary Care.

Resource links provided by NLM:

MedlinePlus related topics: Depression
U.S. FDA Resources

Further study details as provided by University of California, Los Angeles:

Primary Outcome Measures:
  • Severity of depression symptoms [ Designated as safety issue: No ]
    Severity measured by the 21-item Hopkins Symptom Checklist.


Secondary Outcome Measures:
  • Functioning [ Designated as safety issue: No ]
    measured by the Sheehan Health-Related Functioning Index


Enrollment: 1801
Study Start Date: January 1999
Study Completion Date: June 2004
Primary Completion Date: June 2004 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: IMPACT Other: IMPACT
IMPACT is a collaborative care management program for late-life depression
Other Name: Improving Mood-Promoting Access to Collaborative Treatment
No Intervention: Care as Usual
Patients received all depression care available to them as part of care as usual in the participating primary care clinics.

Detailed Description:

This study tested an organized method of delivering care for late life depression in primary care. Specifically, the investigators evaluated the effectiveness of this intervention as compared to 'care as usual'. The investigators studied the effect of the intervention on clinical outcomes such as depressive symptoms, functional status, health related quality of life. They also determined the cost-effectiveness of the intervention compared to care as usual.

  Eligibility

Ages Eligible for Study:   60 Years and older
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • Major depression or dysthymia as diagnosed by a structured diagnostic interview.
  • Patient plans to receive primary care at the study clinic for the next year.

Exclusion Criteria:

  • Age under 60.
  • Current symptoms or history of psychosis or mania as determined by structured diagnostic interview.
  • Cognitive impairment as defined by a score less than 23 on a Mini Mental Status Examination.
  • Terminal illness - defined as having a life expectancy of less than 6 months.
  • Active alcohol abuse as determined by a screening interview.
  • High suicide risk as determined by current plan for suicide or a history of more than 3 prior suicide attempts in the past 10 years.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01561105

Sponsors and Collaborators
University of California, Los Angeles
John A. Hartford Foundation
California HealthCare Foundation
Hogg Foundation
Robert Wood Johnson Foundation
Investigators
Principal Investigator: Jurgen Unutzer, MD, MPH University of Washington
  More Information

Publications:

Responsible Party: Jurgen Unutzer, MD, MPH, Professor and Vice-Chair of Psychiatry, Psychiatry and Behavioral Sciences, University of Washington
ClinicalTrials.gov Identifier: NCT01561105     History of Changes
Other Study ID Numbers: JAHF 98297
Study First Received: March 20, 2012
Last Updated: March 26, 2012
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Depression
Depressive Disorder
Dysthymic Disorder
Depressive Disorder, Major
 Behavioral Symptoms
Mood Disorders
Mental Disorders

ClinicalTrials.gov processed this record on May 19, 2013