Hepcidin Levels in Preterm Infants
A recently isolated peptide hormone, hepcidin, is thought to be the principal regulator of iron homeostasis. Hepcidin acts by limiting intestinal iron absorption and promoting iron retention in reticuloendothelial cells. The aims of this study were to determine serum hepcidin levels in preterm infants who receive blood transfusion and preterm infants having sepsis, in order to assess possible relationships between hepcidin and serum iron, serum ferritin,in iron load situations.
Anemia of Prematurity
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Hepcidin Levels in Preterm Infants Receiving Blood Transfusion and During Sepsis.|
- Increase in Hepcidin levels by 30% [ Time Frame: within 24-72 h ] [ Designated as safety issue: No ]
|Study Start Date:||March 2012|
|Estimated Study Completion Date:||August 2013|
|Estimated Primary Completion Date:||February 2013 (Final data collection date for primary outcome measure)|
preterm infants receiving blood transfusion
preterm infants with neonatal sepsis.
|Contact: Shmuel Arnon, MDfirstname.lastname@example.org|
|Neonatal Intensive Care Unit||Recruiting|
|Kfar-Saba, Israel, 44281|
|Contact: shmuel arnon, MD email@example.com|