Impact and Utility of PET Versus Clinical Score for the Assessment of Inflammatory Activity in Takayasu Arteritis

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Jose Telich, Instituto Nacional de Cardiologia Ignacio Chavez
ClinicalTrials.gov Identifier:
NCT01532167
First received: February 8, 2012
Last updated: March 23, 2012
Last verified: March 2012
  Purpose

The purpose of this study is to demonstrate that [18F]FDG PET is a a better method than clinical and laboratory values for the identification and assessment of inflammatory activity in patients with Takayasu Arteritis (TA), allowing long-term follow-up with a precise evaluation of response to therapy.


Condition
Takayasu Arteritis

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Impact and Utility of Positron Emission Tomography (PET) for the Assessment of Inflammatory Activity Arteritis Versus Clinical Score and Laboratory Values in Takayasu Arteritis: a Cohort Study

Resource links provided by NLM:


Further study details as provided by Instituto Nacional de Cardiologia Ignacio Chavez:

Enrollment: 26
Study Start Date: February 2010
Study Completion Date: February 2011
Primary Completion Date: February 2011 (Final data collection date for primary outcome measure)
Detailed Description:

Inflammatory activity and fibrosis are the main causes of morbidity and mortality in patients with Takayasu arteritis. The investigators objective is to determine the utility of using 18F-FDG PET in the basal evaluation and follow-up of patients and compare the results with Dabague's clinical score.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Patients treated for TA at our institution's immunology outpatient clinic were included between.

Criteria

Inclusion Criteria:

  • TA was diagnosed if the patient met 3 or more ACR criteria.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01532167

Locations
Mexico
Instituto Nacional de Cardiologia
Mexico, DF, Mexico
Sponsors and Collaborators
Instituto Nacional de Cardiologia Ignacio Chavez
Investigators
Principal Investigator: Maria E Soto, MD Instituto Nacional de Cardiologia
Study Director: Erick Alexanderson, MD Instituto Nacional de Cardiologia
  More Information

No publications provided

Responsible Party: Jose Telich, Investigator, Instituto Nacional de Cardiologia Ignacio Chavez
ClinicalTrials.gov Identifier: NCT01532167     History of Changes
Other Study ID Numbers: 12-755
Study First Received: February 8, 2012
Last Updated: March 23, 2012
Health Authority: Mexico: Secretaria de Salud

Additional relevant MeSH terms:
Aortic Arch Syndromes
Arteritis
Takayasu Arteritis
Aortic Diseases
Cardiovascular Diseases
Skin Diseases
Skin Diseases, Vascular
Vascular Diseases
Vasculitis

ClinicalTrials.gov processed this record on October 29, 2014