Susceptibility to Pathological Gambling

This study is currently recruiting participants.
Verified December 2013 by University of Chicago
Information provided by (Responsible Party):
Jon Grant, University of Chicago Identifier:
First received: August 30, 2011
Last updated: December 12, 2013
Last verified: December 2013

The goal of this study is to assess the risk factors for the development of pathological gambling.

Condition Intervention
Pathological Gambling
Behavioral: Mindfulness
Behavioral: Cognition

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
Official Title: Susceptibility to Pathological Gambling

Resource links provided by NLM:

Further study details as provided by University of Chicago:

Primary Outcome Measures:
  • Structured Clinical Interview for Pathological Gambling (SCI-PG) [ Time Frame: Up to 3 years ] [ Designated as safety issue: No ]

    The SCI-PG is a validated and reliable scale assessing the presence of DSM-IV criteria for pathological gambling. The number of criteria met for PG is added for a total score and those meeting 5 or more criteria have DSM-IV pathological gambling.

    Subjects are expected to be followed for the duration of the 3 year study.

    Diagnostic criteria for pathological gambling every 3 months for the length of the study

Estimated Enrollment: 600
Study Start Date: November 2008
Estimated Study Completion Date: September 2015
Estimated Primary Completion Date: September 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: Control
Active Comparator: Mindfulness
Mindfulness activity and psychoeducation
Behavioral: Mindfulness
Subjects receive mindfulness training
Other Name: Training
Active Comparator: Cognition
Cognitive training and psychoeducation
Behavioral: Cognition
Subject receive cognitive training
Other Name: Training

Detailed Description:

This study will track up to 600 young adults (ages 18 to 29) for a two-year period, collecting variables such as gambling behavior, drug and alcohol use, psychiatry and medical history, family history, impulsivity, quality of life, self-esteem, and cognition. For some individuals who meet criteria as being impulsive, they will be randomized to receive an intervention to help reduce their impulsivity.


Ages Eligible for Study:   18 Years to 29 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Ability to understand the procedures and provide written consent
  • Gambled at least 5 times in the past year
  • Between the ages of 18 and 29 at intake

Exclusion Criteria:

  • Inability to understand the procedures and provide written consent
  Contacts and Locations
Please refer to this study by its identifier: NCT01528982

Contact: Katherine L Derbyshire, BS 773-702-9066

United States, Illinois
University of Chicago Recruiting
Chicago, Illinois, United States, 60637
Contact: Jon E Grant, JD, MD, MPH    773-834-1325   
Contact: Katherine L Derbyshire, B.S.    773-702-9066   
Principal Investigator: Jon E Grant, JD, MD, MPH         
Sponsors and Collaborators
University of Chicago
Principal Investigator: Jon E Grant, JD, MD, MPH University of Chicago, Department of Psychiatry
  More Information

No publications provided

Responsible Party: Jon Grant, Profesor of Psychiatry, University of Chicago Identifier: NCT01528982     History of Changes
Other Study ID Numbers: 0811S53121
Study First Received: August 30, 2011
Last Updated: December 12, 2013
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Disease Susceptibility
Disease Attributes
Pathologic Processes
Impulse Control Disorders
Mental Disorders processed this record on April 23, 2014