LUCAS Chest Compressor Versus Manual Chest Compression in Out-of-hospital Sudden Cardiac Arrest. LUCAT Trial

• Survival at hospital admittance [ Time Frame: 2 hours ] [ Designated as safety issue: No ]
  The primary goal is to evaluate survival at hospital admittance of patients, after out-of hospital cardiac arrest treated by LUCAS device chest compressions, compared with those patients treated by manual chest compressions
  
  
• Survival on discharge from hospital (or 30 days if not applicable) in acceptable neurological state (CPC scale 1 or 2) [ Time Frame: 30 days ] [ Designated as safety issue: No ]
  Evaluate the neurological outcome on hospital discharge, in two centres (Vall d'Hebron Hospital in Barcelona and Josep Trueta Hospital in Girona) 1 or 2 in Cerebral Performance Category
  
  

• Restoration of spontaneous circulation [ Time Frame: 2 hours ] [ Designated as safety issue: No ]
  To compare the return of spontaneous circulation (ROSC) between both groups
  
  
• EndTidal CO2 values [ Time Frame: Every four minutes during resuscitation maneuvers ] [ Designated as safety issue: No ]
  To compare EndTidal CO2 values of patients during cardiopulmonary resuscitation (CPR)between boths study arms
  
  
• SOFA scale values [ Time Frame: During the first three days and on hospital discharge ] [ Designated as safety issue: No ]
  To compare the first three days, on hospital discharge SOFA scale value and the worse value obtained (date and hour) in patients who survived out-of-hospital SCA and weere brought to either Vall d'Hebron Hospital or Josep Trueta Hospital.
  
  
• Days before discharge from Intensive Care Unit (ICU) / Coronary Care Unit (CCU) [ Time Frame: 30 days ] [ Designated as safety issue: No ]
  To compare days before discharge from Intensive Care Unit (ICU) / Coronary Care Unit (CCU) in patients who survived out-of-hospital SCA and were brought to either Vall d'Hebron Hospital or Josep Trueta Hospital
  
  
• Metabolic (pH, lactate) and inflamatory (leukocytes, C reactive protein) parameters [ Time Frame: During the first 24h, at >48h and at 5-7days ] [ Designated as safety issue: No ]
  To establish the differences in metabolic (pH, lactate) and inflamatory (leukocytes, C reactive protein) parameters in patients who survived out-of-hospital SCA and were brought to either Vall d'Hebron Hospital or Josep Trueta Hospital
  
  
• Epidemiology of Out-of-Hospital Cardiac Arrest [ Time Frame: 3 months ] [ Designated as safety issue: No ]
  To describe the epidemiology of out-of-hospital SCA in the cities of Barcelona, Girona and Lleida
  
  
• To obtain a blood sample for genetic and biological studies [ Time Frame: 7 days ] [ Designated as safety issue: No ]
  Blood samples from SCA survivors will be kept to perform biological studies.
  
  
• Left ventricular function [ Time Frame: During the first 24h and during the 24h previous on hospital discharge or at two months ] [ Designated as safety issue: No ]
  To compare left ventricular function in patients who survived at out-of-hospital sudden cardiac arrest and were brought to either Vall d'Hebron Hospital or Josep Trueta Hospital
  
  

The primary goals of the trial are:

• To show a survival increase at hospital admittance after out-of-hospital cardiac arrest of patients treated by continuous chest compressions LUCAS device compared with patients treated by manual chest compressions.
• To evaluate neurological outcome on hospital discharge, in two centres (Vall d'Hebron Hospital and Josep Trueta Hospital).