A Russian Prospective Observational Study of Invasive Fungal Infections in Patients With Acute Leukemia and Hematopoietic Stem Cell Transplantation
Estimate the rate of occurrence of Invasive Fungal Infections (IFIs) in patients with acute leukemia for the first 6 months of chemotherapy (that usually correspond to four courses of chemotherapy), and hematopoietic stem cells transplantation.
Invasive Fungal Infections
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||A Russian Prospective Observational Study of Invasive Fungal Infections in Patients With Acute Leukemia and Hematopoietic Stem Cell Transplantation|
- The Rate of Invasive Fungal Infections [ Time Frame: 6 month ] [ Designated as safety issue: No ]Estimate the rate of IFIs in patients with acute leukemia for the first 6 months of chemotherapy (that usually correspond to four courses of chemotherapy), and hematopoietic stem cells transplantation.
|Study Start Date:||January 2012|
|Study Completion Date:||March 2014|
|Primary Completion Date:||September 2013 (Final data collection date for primary outcome measure)|
Acute leukemia patients
Patients with de novo or relapsed acute myeloid and lymphoid leukemia
|Allo- or auto- transplant recipients|
This multi-center observational study of IFI in high risk hematological patients, the study will investigate the epidemiology of IFI, describe antifungal strategy, proportion of antifungal prophylaxis, empiric therapy, pre-emptive therapy and targeted therapy in at-risk patients.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01519648
|National Hematological Society|
|Moscow, Russian Federation, 119021|
|Principal Investigator:||Galina A Klyasova||National Research Center For Hematology|