Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient (O2 Fraction)

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
Swedish Medical Center
ClinicalTrials.gov Identifier:
NCT01513213
First received: January 5, 2012
Last updated: September 17, 2014
Last verified: September 2014
  Purpose

The purpose of this study is to evaluate whether a correlation exists between the partial pressure of carbon dioxide existing within arterial blood and the gradient between inhaled and exhaled fractions of oxygen.


Condition
Neurosurgery

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient

Resource links provided by NLM:


Further study details as provided by Swedish Medical Center:

Primary Outcome Measures:
  • Correlate the level of carbon dioxide within arterial blood to inspired and expired oxygen gradient. [ Time Frame: At least 2 hours ] [ Designated as safety issue: No ]
    Compare the levels of carbon dioxide found in the patient's blood to the amounts of carbon dioxide and oxygen in the air that the patient inhales and exhales. If a relationship exists between the levels of carbon dioxide in the blood and the levels of carbon dioxide and oxygen inhaled and exhaled by the patient, anesthesiologists will be able to use this relationship to adjust ventilators during anesthesia without having to take blood from an artery.


Estimated Enrollment: 50
Study Start Date: October 2011
Estimated Study Completion Date: October 2014
Primary Completion Date: May 2014 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Adults age 18 to 65 scheduled for a surgical procedure that will last at least two hours and for whom arterial cannulation and at least two arterial blood gas analyses are planned during the surgery.

Criteria

Inclusion Criteria:

  • Age 18 to 65.
  • Scheduled for surgical procedure that will last at least 2 hours.
  • Arterial cannulation is planned because of either the complexity of the surgery or patient comorbidity.
  • At least two arterial blood gas analyses are planned during the surgery.

Exclusion Criteria:

  • No arterial cannulation is necessary or planned for the procedure.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01513213

Locations
United States, Washington
Swedish Medical Center
Seattle, Washington, United States, 98122
Sponsors and Collaborators
Swedish Medical Center
Investigators
Principal Investigator: Arthur M Lam, MD, FRCPC Swedish Medical Center
  More Information

No publications provided

Responsible Party: Swedish Medical Center
ClinicalTrials.gov Identifier: NCT01513213     History of Changes
Other Study ID Numbers: 5119S-11
Study First Received: January 5, 2012
Last Updated: September 17, 2014
Health Authority: United States: Institutional Review Board

Keywords provided by Swedish Medical Center:
Arterial cannulation
Blood gas
Carbon dioxide
Arterial blood
Oxygen
Oxygen fractions

ClinicalTrials.gov processed this record on October 28, 2014