Assessing Perceived Versus Actual Knowledge and Quality of Life in Pre-Dialysis Chronic Kidney Disease (CKD) Patients

This study is currently recruiting participants. (see Contacts and Locations)
Verified August 2013 by National University, Singapore
Sponsor:
Information provided by (Responsible Party):
Priscilla How, Pharm.D., BCPS, National University, Singapore
ClinicalTrials.gov Identifier:
NCT01509716
First received: January 6, 2012
Last updated: August 19, 2013
Last verified: August 2013
  Purpose

Aims: The investigators' primary objective is to assess both perceived and actual disease knowledge in local pre-dialysis Chronic Kidney Disease (CKD) patients. The investigators hypothesize that actual disease knowledge is poorer than perceived. As the secondary objectives, the investigators will also assess the HRQoL and examine the association between level of knowledge and HRQoL in pre-dialysis CKD patients. The investigators hypothesize that HRQoL of pre-dialysis CKD patients is poorer than that of the general population while pre-dialysis CKD patients with greater disease knowledge have a better HRQoL than those with poorer knowledge.

Methodology: A survey was developed to assess both perceived and actual knowledge on five aspects - general knowledge, nephrotoxic medications, diet restrictions, symptoms of CKD and its complications and renal replacement therapy (RRT) options. For the assessment of HRQoL, the following questionnaires will be used - Kidney Disease Quality of Life-Short Form (KDQOL-SF) version 1.3, EuroQoL 5 Dimensions (EQ-5D), Family Functioning Measure (FFM), and Oslo-3 Social Support Scale (OSS-3). All study questionnaires will be provided in 3 main languages - English, Chinese and Malay. A standardized data collection form was developed to retrospectively collect demographic and clinical information from the patients' electronic medical records and patient charts. Descriptive statistics will be used to report all results.


Condition
Chronic Kidney Disease Stage 3
Chronic Kidney Disease Stage 4
Chronic Kidney Disease Stage 5

Study Type: Observational
Study Design: Time Perspective: Cross-Sectional
Official Title: Assessing Perceived Versus Actual Knowledge and Quality of Life in Pre-Dialysis CKD Patients

Resource links provided by NLM:


Further study details as provided by National University, Singapore:

Estimated Enrollment: 400
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Predialysis patients with stage 3-5 chronic kidney disease patients seen in outpatient renal clinic in National University Hospital, Singapore

Criteria

Inclusion Criteria:

  • patients at least 21 years of age,
  • able to read English, Chinese or Malay,
  • have stage 3 to 5 CKD as identified from their medical records, but are not receiving dialysis.

Exclusion Criteria:

  • patients who do not consent,
  • have already been started on dialysis,
  • are cognitively impaired as assessed by the recruiter or unable to fill up questionnaires on their own.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01509716

Contacts
Contact: Priscilla P How, Pharm.D. (65) 6516 4906 priscillahow@nus.edu.sg

Locations
Singapore
National University Hospital Recruiting
Singapore, Singapore
Contact: Priscilla P How, Pharm.D.    (65) 6516 4906    priscillahow@nus.edu.sg   
Principal Investigator: Priscilla P How, Pharm.D.         
Sponsors and Collaborators
National University, Singapore
  More Information

No publications provided

Responsible Party: Priscilla How, Pharm.D., BCPS, Assistant Professor, National University, Singapore
ClinicalTrials.gov Identifier: NCT01509716     History of Changes
Other Study ID Numbers: DSRB Domain E/2011/02008
Study First Received: January 6, 2012
Last Updated: August 19, 2013
Health Authority: Singapore: Health Sciences Authority

Keywords provided by National University, Singapore:
Predialysis

Additional relevant MeSH terms:
Kidney Diseases
Renal Insufficiency, Chronic
Urologic Diseases
Renal Insufficiency

ClinicalTrials.gov processed this record on September 15, 2014