Effect of Ingestion of Sugary Drinks on Thirst Sensation

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Pedro Miguel Fernandes Ramos de Carvalho, Universidade do Porto
ClinicalTrials.gov Identifier:
NCT01502722
First received: November 22, 2011
Last updated: January 15, 2013
Last verified: January 2013
  Purpose

The purpose of this study is to determine if regular soft drinks (with sugar) have the same effect on thirst as diet soft drinks(with sweeteners).


Condition Intervention
Thirst
Behavioral: Effect of ingestion sugary and sweetened drinks on thirst

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Primary Purpose: Diagnostic
Official Title: Effect of Ingestion of Sugary Drinks on Thirst Sensation

Resource links provided by NLM:


Further study details as provided by Universidade do Porto:

Primary Outcome Measures:
  • Motivational Ratings [ Time Frame: 1 day ] [ Designated as safety issue: No ]
    Participants will rate their hunger, thirst, nausea, mouth dryness, desire to eat, desire to drink using nine point category scales. The unipolar adjective scales were anchored at each end with labels: 1 = not at all and 9 = extremely. Participants also rated their liking for the beverage along nine point hedonic preference scales where 1 = dislike extremely and 9 = like extremely


Secondary Outcome Measures:
  • Food Behavior After Intervention [ Time Frame: 1 day ] [ Designated as safety issue: No ]
    After lunch, participants will bring a food diary to record all food and fluid intake until 00.00 that day. Then, we will analyse total calories ingested, total fluid ingested and the volume of sugar and sugary beverages ingested.

  • Amount of water ingested [ Time Frame: 1 day ] [ Designated as safety issue: No ]
    After the ingestion of 3 preloads with the beverages in study (water, pineapple soda and pineapple diet soda), the participants will lunch the same meal bu the water ingestion will be ad libitum.


Enrollment: 24
Study Start Date: January 2012
Study Completion Date: August 2012
Primary Completion Date: February 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Group 1 - Crossover
This group will drink water in the 1st study.
Behavioral: Effect of ingestion sugary and sweetened drinks on thirst
The participants will drink Water (control group), Decarbonized Pineapple Soda (11% sugar)and Decarbonized Pineapple Diet Soda (1% Sugar and Sucralose). The beverages will be presented chilled but without ice in 500 ml portions in opaque plastic containers and participants will be asked to consume the entire amount within 15 min. The beverages will be tested previously in laboratory in order to obtain their pH and osmolality.
Other Names:
  • Effect of ingestion of water, soda and diet soda on thirst
  • Diferences between sweeteners and sugar on thirst
Experimental: Group 2 - Crossover
This group will drink Pineapple Soda in the 1st study
Behavioral: Effect of ingestion sugary and sweetened drinks on thirst
The participants will drink Water (control group), Decarbonized Pineapple Soda (11% sugar)and Decarbonized Pineapple Diet Soda (1% Sugar and Sucralose). The beverages will be presented chilled but without ice in 500 ml portions in opaque plastic containers and participants will be asked to consume the entire amount within 15 min. The beverages will be tested previously in laboratory in order to obtain their pH and osmolality.
Other Names:
  • Effect of ingestion of water, soda and diet soda on thirst
  • Diferences between sweeteners and sugar on thirst
Experimental: Group 3 - Crossover
This group will drink Pineapple Diet Soda in the 3rd study
Behavioral: Effect of ingestion sugary and sweetened drinks on thirst
The participants will drink Water (control group), Decarbonized Pineapple Soda (11% sugar)and Decarbonized Pineapple Diet Soda (1% Sugar and Sucralose). The beverages will be presented chilled but without ice in 500 ml portions in opaque plastic containers and participants will be asked to consume the entire amount within 15 min. The beverages will be tested previously in laboratory in order to obtain their pH and osmolality.
Other Names:
  • Effect of ingestion of water, soda and diet soda on thirst
  • Diferences between sweeteners and sugar on thirst

Detailed Description:

Participants should be in the laboratory at 8.00 in order to collect the values of weight, height, total body water, intracellular water and extracellular water in a Segmental Multi Frequency Body Composition Monitor (TANITA MC 180 MA®). Then, a blood sample will be collected for analysis of blood glucose and osmolality. They will sit at individual tables for the duration of the session and were allowed to read, listen to music with earphones, or use their portable computers with the exception of internet access to minimize visual cues (e.g., unwanted publicity for beverages or visiting Web sites showing pictures of food and drinks), which may have effect on thirst. Breakfast will be served at 9.30 on every occasion and preload stimuli will be offered exactly 60 minutes after breakfast (at 10.30). Lunch will be provided at 13.00. Motivational ratings will be first obtained at the end of collection of blood sample (baseline or time 0) and every 30 minutes thereafter until the lunch time (times 1 through 7). After lunch (time 8), participants will complete the last set of ratings and will bring a food diary to record all food and fluid intake until 00.00 that day.

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • body mass index(BMI) between (18,5 - 25 kg/m2)
  • regular consumers of breakfast
  • stable in weight for the past 6 months
  • not dieting to gain or lose weight
  • like all drinks and food available in study

Exclusion Criteria:

  • pregnant and nursing women
  • smokers
  • athletes
  • subjects under medication(except oral contraceptives in women)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01502722

Locations
Portugal
Faculdade de Ciências da Nutrição e Alimentação da Universidade do Porto
Porto, Portugal, 4200-465
Sponsors and Collaborators
Universidade do Porto
Investigators
Principal Investigator: Pedro R Carvalho, PhD Student Faculdade de Ciências da Nutrição e Alimentação - Universidade do Porto
Study Director: Vitor H Teixeira, PhD Faculdade de Ciências da Nutrição e Alimentação - Universidade do Porto
  More Information

Additional Information:
Publications:
Responsible Party: Pedro Miguel Fernandes Ramos de Carvalho, Principal Investigator, Universidade do Porto
ClinicalTrials.gov Identifier: NCT01502722     History of Changes
Other Study ID Numbers: IHS/FCNAUP-001
Study First Received: November 22, 2011
Last Updated: January 15, 2013
Health Authority: Portugal: Health Ethic Committee

ClinicalTrials.gov processed this record on August 28, 2014