Pain Prevalence After Major Craniotomy
Craniotomies are generally thought to be less painful than other operations. Indeed recent studies have confirmed that pain is a common problem during the postoperative phase following craniotomy.Pain not only causes discomfort, but it is also associated with other potential adverse events such as increased sympathetic activity and elevated systemic blood pressure. These events in turn may contribute to increased intracranial pressure. Some patients may also develop chronic pain.Potent opioids have been avoided due to its potential to cause respiratory depression and risk of masking pupillary signs. As a result postoperative craniotomy pain controls are usually inadequate.
In Siriraj hospital, there are 500-600 craniotomy patients per year. Still there are no definite guidelines for postoperative pain management in these patents due to lack of information about quality of postoperative pain control after craniotomy.
Primary objective :
- To study incidence of moderate to severe pain during first 48 hours after craniotomy.
Secondary objectives :
- To determine risk factors for moderate to severe pain during first 48 hours after craniotomy
- To evaluate side effects and complications of postoperative craniotomy pain control
- To compare patient's expectation for pain management before and after surgery
- To determine patient's satisfaction for postoperative pain management
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Pain Prevalence After Major Craniotomy in Siriraj Hospital|
- incidence of moderate to severe pain following major craniotomy [ Time Frame: 48 hours ] [ Designated as safety issue: Yes ]
- risk factors of moderate to severe pain following craniotomy. [ Time Frame: 48 hours ] [ Designated as safety issue: Yes ]
|Study Start Date:||October 2010|
|Study Completion Date:||January 2013|
|Primary Completion Date:||January 2013 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01502540
|Bangkok, Thailand, 10700|
|Principal Investigator:||Sirilak Suksompong, MD||Mahidol University|