Biomarkers in Tumor Tissue Samples From Younger Patients With Rhabdomyosarcoma
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PURPOSE: This research trial studies biomarkers in tumor tissue samples from younger patients with rhabdomyosarcoma.
Genetic: gene expression analysis
Genetic: microarray analysis
Other: laboratory biomarker analysis
|Official Title:||CRKL Expression at the Protein Level in Rhabdomyosarcoma Tumors by Tissue Microarray (TMA)|
- CRKL expression at the protein level [ Designated as safety issue: No ]
|Study Start Date:||December 2011|
|Estimated Primary Completion Date:||February 2012 (Final data collection date for primary outcome measure)|
- To demonstrate CRKL expression at the protein level in rhabdomyosarcoma tumors by tissue microarray (TMA).
OUTLINE: Archived tumor tissue samples are analyzed for CRKL expression.
|Principal Investigator:||Lee J. Helman, MD||National Cancer Institute (NCI)|