Polscope Sperm: A Non-invasive Method to Assess DNA Damage in Individual Sperm
The purpose of this study is to find a non-invasive way to discover DNA (deoxyribonucleic acid, which is the genetic material inside your cells) alterations in the sperm's head, in the near future leading us to choose the "good sperm" in a simplified manner. This could then increase chances of a successful in-vitro fertilization (IVF) treatment when there are sperm abnormalities.
Other Complications Associated With Artificial Fertilization
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||A Non-invasive Method to Assess DNA Damage in Individual Sperm|
|Study Start Date:||October 2008|
|Study Completion Date:||June 2012|
|Primary Completion Date:||June 2012 (Final data collection date for primary outcome measure)|
If you take part in this study,
- Your physician is asking you to provide a semen sample as you already would. The sample will be taken to the IVF lab which would occur if you were not involved in this research. The part that would be thrown away is then further analyzed under a polarized light microscope. The sample is exposed to ultraviolet (UV) light for a period of 20 minutes after which it is analyzed under the microscope again, looking for any changes when compared the sample that was not exposed to UV light. The sample is then discarded.
- Your name will be removed from the sample after the regular semen analysis is done; therefore there will be no way of associating the research results with you. No information will be needed from you and you will not be contacted in the future regarding this research.
|United States, Florida|
|University of South Florida South Tampa Center|
|Tampa, Florida, United States, 33606|
|Principal Investigator:||Celso Silva, M.D||University of South Florida|