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Cancer Genome Analysis

This study is currently recruiting participants.
Verified October 2011 by Seoul National University Hospital
Sponsor:
Information provided by (Responsible Party):
Seoul National University Hospital
ClinicalTrials.gov Identifier:
NCT01458704
First received: October 23, 2011
Last updated: October 24, 2011
Last verified: October 2011
History of Changes
  Purpose

Next generation sequencing (including targeted gene seqeuncing, exome and transcriptome sequencing) will be performed from fresh frozen tumor samples to understand the genetic alteration of tumors and to aid in optimal selection of further therapeutic agents.


Condition Intervention
Malignant Tumor
 Other: next generation sequencing

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Cancer Genome Analysis

Resource links provided by NLM:

MedlinePlus related topics: Cancer
U.S. FDA Resources

Further study details as provided by Seoul National University Hospital:

Primary Outcome Measures:
  • targeted sequencing of cancer-relate genes [ Time Frame: 1 year ] [ Designated as safety issue: No ]
    Identification and characterization of genetic alteration in cancer tissue


Biospecimen Retention:   Samples With DNA

fresh frozen tumor tissue


Estimated Enrollment: 100
Study Start Date: August 2011
Estimated Primary Completion Date: April 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
fresh frozen tumor tissue
patients providing fresh frozen tumor tissue
 Other: next generation sequencing
next generation sequencing (including targeted gene sequencing, exome sequencing, transcriptome sequenicing)

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

patients with malignant tumor receiving or planning to receive chemotherapy with fresh frozen tumor tissue with informed consent

Criteria

Inclusion Criteria:

  • patients with malignant tumor
  • receiving or planning to receive chemotherapy
  • with fresh frozen tumor tissue
  • with informed consent
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01458704

Contacts
Contact: Tae-You Kim 82-2-2072-2228

Locations
Korea, Republic of
Seoul National University Hospital Recruiting
Seoul, Korea, Republic of, 110-744
Contact: Tae-You Kim     82-2-2072-2228     kimty@snu.ac.kr    
Sponsors and Collaborators
Seoul National University Hospital
Investigators
Principal Investigator: Tae-You Kim Seoul National University Hospital
  More Information

No publications provided

Responsible Party: Seoul National University Hospital
ClinicalTrials.gov Identifier: NCT01458704     History of Changes
Other Study ID Numbers: Cancer genome analysis
Study First Received: October 23, 2011
Last Updated: October 24, 2011
Health Authority: Republic of Korea: Food and Drug Administration

Additional relevant MeSH terms:
Neoplasms

ClinicalTrials.gov processed this record on May 21, 2013