Prevalence of Pulmonary Embolism in ICU (PEICU)
The primary objective of this study was to estimate the prevalence of PE among consecutive ICU patients receiving MV who required thoracic computed tomography (CT) with contrast agent injection, regardless of whether PE was suspected clinically. The secondary objectives were to assess the association between PE and DVT, to identify risk factors for VTE, and to determine the outcome of VTE.
Deep Venous Thrombosis
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Pulmonary Embolism in Mechanically Ventilated Patients Requiring Computed Tomography: Prevalence, Risk Factors and Outcome|
- Find a pulmonary embolism on the CT scan [ Time Frame: CT scan at the day of inclusion ] [ Designated as safety issue: No ]TO estimate the prevalence of PE among consecutive ICU patients receiving MV who required thoracic computed tomography (CT) with contrast agent injection, regardless of whether PE was suspected clinically.
- To find thrombus on compression ultrasound (CUS) of the four limbs [ Time Frame: CUS within 48 hours after the CT scan ] [ Designated as safety issue: No ]
|Study Start Date:||December 2009|
|Study Completion Date:||April 2011|
|Primary Completion Date:||April 2011 (Final data collection date for primary outcome measure)|
|pulmonary embolism, deep venous thrombosis|
Background: Pulmonary embolism (PE) produces nonspecific or minimal symptoms in mechanically ventilated (MV) patients, leading to underdiagnosis. We estimated the prevalence of PE and associations with deep vein thrombosis (DVT) among MV patients.
Methods: Consecutive MV patients who required thoracic computed tomography (CT) in a single ICU. Compression ultrasound of the four limbs was performed within 48 hours of inclusion. Curative anticoagulation therapy was given immediately after PE diagnosis.
|University hospital of grenoble|
|Grenoble, France, 38043|
|Principal Investigator:||Jean Francois TIMSIT, PU/PH||University Hospital, Grenoble|