Relationship Between Tissue Markes in Patients With Post Cardio Respiratory Syndrome

The recruitment status of this study is unknown because the information has not been verified recently.
Verified November 2011 by Hospital Nossa Senhora da Conceicao.
Recruitment status was  Recruiting
Sponsor:
Information provided by (Responsible Party):
Vanessa Martins de oliveira, Hospital Nossa Senhora da Conceicao
ClinicalTrials.gov Identifier:
NCT01455662
First received: September 28, 2011
Last updated: November 2, 2011
Last verified: November 2011
  Purpose

There is a correlation between hospital mortality and changes in markers of tissue perfusion, lactate, and venous oxygen saturation and carbon dioxide gradient.


Condition
Cardiac Arrest

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Relationship Between Lactate and Venous Oxygen Saturation Gradient of Carbon Dioxide in Patients With Post Cardio Respiratory Syndrome

Resource links provided by NLM:


Further study details as provided by Hospital Nossa Senhora da Conceicao:

Primary Outcome Measures:
  • mortality [ Time Frame: 1 year ] [ Designated as safety issue: Yes ]

Secondary Outcome Measures:
  • correlation of clearance markers of perfusion with the use of vasopressor and positive fluid balance [ Time Frame: 6 hours ] [ Designated as safety issue: Yes ]

Estimated Enrollment: 100
Study Start Date: January 2010
Estimated Study Completion Date: December 2011
Estimated Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
all patients after cardiac arrest

Detailed Description:

Evaluation of the serum carbon dioxide gradient (GapCO2), central venous saturation (ScvO2) and the clearance of serum lactate (Clac) in predicting hospital mortality after cardiac arrest syndrome (post-PCR).

Prospective study, unicenter - Intensive Care Unit - HNSC. Period: May/2010 to June/2011. Serial assessment of GapCO2 of ScvO2 Clac and the first 72 hours post-PCR. Excluded under 18, survival of less than 6HS, pregnant women, traumatized, post-operative hypothermia and liver disease. T-student test, 95% (p <0.05).

  Eligibility

Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

patients hospitalized in the intensive care unit after cardiopulmonary arrest

Criteria

Inclusion Criteria:

  • All patients hospitalized in the intensive care unit after cardiopulmonary arrest with any pace

Exclusion Criteria:

pregnant women, traumatized, post-operative(less 7 days), hypothermia and liver disease.

  • patients hospitalized in the intensive care unit with more than 6 hours post cardiac arrest
  • less 18 years old
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01455662

Contacts
Contact: Vanessa M Oliveira, MD 05192513723 vanessa.oliveira480@gmail.com
Contact: Diego Riveiro, MD 05184175632 dmriveiro@yahoo.com.br

Locations
Brazil
Conceição Hospital Recruiting
Porto Alegre, Rio Grande do Sul, Brazil
Principal Investigator: Vanessa Oliveira, MD         
Principal Investigator: Diego Riveiro, MD         
Sponsors and Collaborators
Hospital Nossa Senhora da Conceicao
Investigators
Principal Investigator: Vanessa Oliveira, MD Conceição Hospital
Principal Investigator: Diego F Riveiro, MD Hospital Nossa Senhora da Conceição
  More Information

No publications provided

Responsible Party: Vanessa Martins de oliveira, Principal Investigator, Hospital Nossa Senhora da Conceicao
ClinicalTrials.gov Identifier: NCT01455662     History of Changes
Other Study ID Numbers: 10086
Study First Received: September 28, 2011
Last Updated: November 2, 2011
Health Authority: Brazil: Ethics Committee

Keywords provided by Hospital Nossa Senhora da Conceicao:
cardiac arrest

Additional relevant MeSH terms:
Heart Arrest
Heart Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on August 28, 2014