Genetic Contribution of Pain and Inflammation in IBS

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Florida
ClinicalTrials.gov Identifier:
NCT01436760
First received: September 16, 2011
Last updated: March 23, 2012
Last verified: March 2012
  Purpose

The goal of the study is to identify possible polymorphisms on the loci of candidate genes that may be involved in modulation of pain and inflammation in irritable bowel syndrome.


Condition
Irritable Bowel Syndrome

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Genetic Contribution of Pain and Inflammation in Irritable Bowel Syndrome.

Further study details as provided by University of Florida:

Primary Outcome Measures:
  • Polymorphisms [ Time Frame: one year ] [ Designated as safety issue: No ]
    The goal of the study isd to identify possible polymorphisms on the loci of canidate genes that may be involved in modulation of pain and inflammation in irritable Bowel Syndrome.


Biospecimen Retention:   Samples With DNA

The delinked blood/DNA is stored in the genetics laboratory and they will be analyzed for possible polymorphisms


Enrollment: 72
Study Start Date: May 2011
Study Completion Date: March 2012
Primary Completion Date: March 2012 (Final data collection date for primary outcome measure)
Detailed Description:

Stored and de-linked blood or DNA from subjects with IBS will be utilized for analysis for possible polymorphisms at predetermined genetic loci located in chosen genes.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

Generic laboratory blood bank

Criteria

Inclusion Criteria:

  • Subjects with IBS and previously stored samples

Exclusion Criteria:

  • Subjects without IBS and no previously stored samples
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01436760

Locations
United States, Florida
University of Florida
Gainesville, Florida, United States, 32610
Sponsors and Collaborators
University of Florida
Investigators
Principal Investigator: Baharak Moshiree, MD, MS University of Florida
  More Information

No publications provided

Responsible Party: University of Florida
ClinicalTrials.gov Identifier: NCT01436760     History of Changes
Other Study ID Numbers: 132-2011
Study First Received: September 16, 2011
Last Updated: March 23, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by University of Florida:
IBS

Additional relevant MeSH terms:
Inflammation
Irritable Bowel Syndrome
Pathologic Processes
Colonic Diseases, Functional
Colonic Diseases
Intestinal Diseases
Gastrointestinal Diseases
Digestive System Diseases

ClinicalTrials.gov processed this record on July 24, 2014