Gastrointestinal Microcirculation During Cardiopulmonary Bypass
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Purpose
O2C is a diagnostic device for non-invasive determination of oxygen supply in microcirculation of blood perfused tissues. The optical sensor is easy to handle and guarantees reproducible examinations of local oxygen supply of tissues in clinics as well as in research. The examinations are without any strain for your patient.
Determines by use of a glass fibre probe:
Blood Flow in Microcirculation Capillary-Venous Oxygen Saturation Blood Filling of Microvessels Blood Flow Velocity This device makes it possible to supervise the local oxygen supply of organs and tissue.
With it is possible to measure locally the amount of oxygen which is transported into the region of interest and to diagnose local oxygen consumption of an organ. O2C's novelty is monitoring the energetic metabolism of cells by measuring the oxygen uptake with an optical sensor probe. Pathological O2-supply, which can lead to angiogenesis or cell-death and subsequently to organ failure, now can be detected in an early state by use of the new sensor system.
One of these new developed sensors are used to place in rectal position during extracorporeal circulation to determine the microcirculation.
| Condition | Intervention |
|---|---|
|
MeSH Heading Cardiac Surgical Procedures Tree Number E04.100.376 Tree Number E04.928.220 |
Procedure: Heart Lung machine |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Prospective |
- Blood Flow in Microcirculation [ Time Frame: 3 hours ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 50 |
| Study Start Date: | June 2012 |
| Groups/Cohorts | Assigned Interventions |
|---|---|
|
Extracorporeal circulation
all patients were measured by microcirculation device O2C
|
Procedure: Heart Lung machine
measurement of microcirculation with O2C device
|
Eligibility| Ages Eligible for Study: | 18 Years to 80 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Probability Sample |
Cardiac surgery patients with ecc
Inclusion Criteria:
- Patients on extracorporeal circulation
Exclusion Criteria:
- Haemorrhoidal lesions
Contacts and Locations| Contact: Arndt H Kiessling, MD | +4969630187015 | cardiac.surgeon@dr-kiessling.com |
| Germany | |
| Goethe University | Recruiting |
| Frankfurt am Main, Hessen, Germany, 60590 | |
| Contact: Arndt H Kiessling, MD +4969630187015 cardiac.surgeon@dr-kiessling.com | |
| Principal Investigator: Arndt H Kiessling, MD | |
More Information
No publications provided
| Responsible Party: | Arndt-H. Kiessling, Head cardiovascular research, Johann Wolfgang Goethe University Hospitals |
| ClinicalTrials.gov Identifier: | NCT01425931 History of Changes |
| Other Study ID Numbers: | O2C-001AHK |
| Study First Received: | August 23, 2011 |
| Last Updated: | June 8, 2012 |
| Health Authority: | Germany: Ethics Commission |
ClinicalTrials.gov processed this record on May 19, 2013