The Effect of a Diabetic- and a Kidney-like Environment on Gene and Protein Expression in Cultured EC and SMC

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
Meir Medical Center
ClinicalTrials.gov Identifier:
NCT01423279
First received: August 24, 2011
Last updated: September 10, 2014
Last verified: February 2013
  Purpose

This research is NOT part of an interventional trial, however the investigators use umbilical cord after birth for isolating endothelial and smooth muscle cells for academic research.


Condition
Endothelial Dysfunction
Disorder of Smooth Muscle

Study Type: Observational
Official Title: The Effect of a Diabetic- and a Kidney-like Environment on Gene and Protein Expression in Mono- and Co-cultured Endothelial and Smooth Muscle Cells

Further study details as provided by Meir Medical Center:

Primary Outcome Measures:
  • The effect of a Diabetic- and a Kidney-like environment on gene and protein expression in mono- and co-cultured endothelial and smooth muscle cells [ Time Frame: one year ] [ Designated as safety issue: No ]

Estimated Enrollment: 20
Study Start Date: February 2013
Estimated Study Completion Date: August 2015
Estimated Primary Completion Date: April 2015 (Final data collection date for primary outcome measure)
Detailed Description:

Isolation and culturing of endothelial and smooth muscle muscles for academic research

  Eligibility

Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

Women after normal birth

Criteria

Inclusion Criteria:

  • normal pregnancy

Exclusion Criteria:

-

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01423279

Locations
Israel
Laboratory of Renal Physiology, Meir Medical Center ,
Kfar Saba, Israel
Sponsors and Collaborators
Meir Medical Center
Investigators
Study Director: Sydney Benchetrit, MD Nephrology dept. Meir Medical Center, Kfar Saba , Israel