The Effect Of A Neurodynamic Treatment On Nerve Conduction In Clients With Low Back Pain

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
McMaster University
ClinicalTrials.gov Identifier:
NCT01402895
First received: July 22, 2011
Last updated: February 7, 2012
Last verified: July 2011
  Purpose

The purpose of this study is to determine if a certain treatment for low back pain can change the way nerves in the leg send messages. Specifically, the investigators will examine whether a particular type of physical therapy treatment for individuals with low back pain (neurodynamic techniques) changes the speed that nerves send/receive signals to/from the leg, as compared to a different physical therapy treatment.


Condition Intervention
Low Back Pain
Other: Exercise
Other: Mobilizations

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: The Effect Of A Neurodynamic Treatment On Nerve Conduction In Clients With Low Back Pain

Resource links provided by NLM:


Further study details as provided by McMaster University:

Primary Outcome Measures:
  • Change in nerve conduction studies [ Time Frame: Change from baseline after intervention, on average 1.5 hours after baseline measure ] [ Designated as safety issue: No ]
    Motor conduction of the tibial nerve; Sensory conduction of the sural nerve; H-reflex, H:M ratio (soleus muscle)


Secondary Outcome Measures:
  • Change of knee extension in sitting slump test [ Time Frame: Change from baseline after intervention, on average 1.5 hours after baseline measure ] [ Designated as safety issue: No ]
  • Change in score of Visual Analog Scale for pain [ Time Frame: Change from baseline after intervention, on average 1.5 hours after baseline measure ] [ Designated as safety issue: No ]

Enrollment: 9
Study Start Date: May 2011
Study Completion Date: October 2011
Primary Completion Date: October 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Mobilizations
The physiotherapist will perform mobilizations to the L-spine and SI joints with the participant in a specific position.
Other: Mobilizations
The physiotherapist will perform mobilizations to the L-spine and SI joints with the participant in a specific position.
Active Comparator: Exercise
The physiotherapist will teach the participant how to tighten the transversus abdominus muscle. The participant will be asked to do a series of these exercises.
Other: Exercise
Transversus abdominus exercise

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Males and females aged 18 years and older
  • Participants who can speak English and read, understand, and fill out the consent form and questionnaires
  • Participants will have a certain level of low back pain graded numerically, with or without radiation to the leg
  • Clinical decision (by same individual) as safe to participate in study based on subjective history and objective examination.

Exclusion Criteria:

  • An inability to tolerate sitting for 10 minutes
  • Nerve conduction disorders diagnosed by a physician such as, diabetes or MS
  • Current participant in an investigational drug study (within past 3 months)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01402895

Locations
Canada, Ontario
McMaster University
Hamilton, Ontario, Canada
Sponsors and Collaborators
McMaster University
Investigators
Study Director: Victoria Galea, PhD McMaster University
Study Chair: Joy MacDermid, PhD McMaster University
Study Chair: Linda Woodhouse, PhD University of Alberta
Study Chair: Anita Gross, MSc McMaster University
  More Information

Publications:
Cyriax, J. (1942). Perineuritis. British Medical Journal, May 9, 578-580.
DeLeo, J.A. (2006). Basic Science Of Pain. The Journal Of Bone And Joint Surgery, 88A Supplement 2, 58-62.

Responsible Party: McMaster University
ClinicalTrials.gov Identifier: NCT01402895     History of Changes
Other Study ID Numbers: 10-541
Study First Received: July 22, 2011
Last Updated: February 7, 2012
Health Authority: Canada: Ethics Review Committee

Keywords provided by McMaster University:
Nerve conduction
H-reflex, mobilizations
with neurodynamic component

Additional relevant MeSH terms:
Low Back Pain
Back Pain
Pain
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms

ClinicalTrials.gov processed this record on September 16, 2014