The Telomere System in Cord Blood and in the Placenta in High Risk Pregnancies
The telomere system stabilizes the chromosomes. Telomeres are shortened during senescence, in cases of genetic instability and secondary to stress.
The investigators aim is to study the telomere system in cord blood and in the placenta immediately after the delivery in pregnancies defined as high risk pregnancies following sterss events such as placental insufficiency, preeclampsia, diabetes.
The investigators intend to compare the telomere system in maternal blood to cord blood and to placental biopsies and to study the influence of different stressogenes on this system.
Mechanisms of Telomter Homeostasis
High Risk Pregnancies
|Study Design:||Observational Model: Case Control
Time Perspective: Cross-Sectional
|Official Title:||The Telomere System in Cord Blood and in the Placenta in High Risk Pregnancies|
|Study Start Date:||June 2011|
|Estimated Study Completion Date:||June 2015|
|Estimated Primary Completion Date:||June 2015 (Final data collection date for primary outcome measure)|
|High risk pregnancy|
||Control - Normal low risk pregnancies|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01384136
|Meir Medical Center|
|Kfar Saba, Israel|