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Effect Of Piperine In Patients With Oropharyngeal Dysphagia (FIS 2009_2)

This study has been completed.
Sponsor:
Information provided by:
Hospital de Mataró
ClinicalTrials.gov Identifier:
NCT01383694
First received: June 27, 2011
Last updated: September 5, 2012
Last verified: September 2012
History of Changes
  Purpose

Piperine acts on the oropharyngeal TRPV1, increasing sensory input and the release of substance P. These actions may accelerate the oropharyngeal swallow response, improving the swallowing of dysphagic patients.


Condition Intervention
Deglutition Disorders
 Drug: Piperine

Study Type: Interventional
Official Title: Effect of Natural Agonists of TRPV1 in the Treatment of Functional Oropharyngeal Dysphagia in Neurological Diseases and the Elderly: Piperine

Resource links provided by NLM:

Drug Information available for: Piperine
U.S. FDA Resources

Further study details as provided by Hospital de Mataró:

Arms Assigned Interventions
Experimental: Piperine Dose 1 Drug: Piperine
Experimental: Piperine Dose 2 Drug: Piperine

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Age>18
  • History of swallowing difficulties associated with aging and/or neurological diseases (neurodegenerative or non-progressive neurological diseases)
  • Study explained and written subject information given
  • Informed consent signed

Exclusion Criteria:

  • Patients suffering idiosyncratic phenomena or who are allergic to any medication, especially iodinated contrast media
  • Patients suffering major respiratory disease or undergoing any type of surgery in the three months prior to the study
  • Patients with a background of alcohol dependence or other drug dependence
  • Currently participating or having participated in another clinical trial during the last 4 weeks prior to the beginning of the study
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01383694

Locations
Spain
Hospital de Mataró
Mataró, Barcelona, Spain, 08304
Sponsors and Collaborators
Hospital de Mataró
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT01383694     History of Changes
Other Study ID Numbers: FIS 22/09
Study First Received: June 27, 2011
Last Updated: September 5, 2012
Health Authority: Spain: Ethics Committee

Additional relevant MeSH terms:
Deglutition Disorders
Esophageal Diseases
Gastrointestinal Diseases
 Digestive System Diseases
Pharyngeal Diseases
Otorhinolaryngologic Diseases

ClinicalTrials.gov processed this record on May 19, 2013