Pulmonary Hypertension, Quality of Life and Psychosocial Factors

• Descriptive analysis of psychological characteristics on PAH patients [ Time Frame: 36 months ] [ Designated as safety issue: No ]
  The descriptive analysis of psychological characteristics (anxiety, depression, social support, coping, control beliefs) is evaluated at entry and at one year. These psychological characteristics are evaluated by score of psychological questionnaires.
  
  

• Psychological characteristics impact on Quality of life [ Time Frame: 36 months ] [ Designated as safety issue: No ]
  The quality of life is measured by the score of the SF 36, the stage of the disease is codified by the NYHA, Qualitative and quantitative analysis of contents of the audio bands by the psychologist implicated to this study.
  
  
• Association between disease and Quality of life evolution [ Time Frame: 36 months ] [ Designated as safety issue: No ]
  The quality of life is measured by the score of the SF 36, the stage of the disease is codified by the NYHA, Qualitative and quantitative analysis of contents of the audio bands by the psychologist implicated to this study.
  
  
• Variability of Quality of life parameters over severity class changes and follow-up [ Time Frame: 36 months ] [ Designated as safety issue: No ]
  The quality of life is measured by the score of the SF 36, the stage of the disease is codified by the NYHA, Qualitative and quantitative analysis of contents of the audio bands by the psychologist implicated to this study.
  
  

PAH is a rare, and severe disease, potentially mortal, affecting preferentially young subjects. The knowledge and the international literature, as regards the quality of life, the expectations, the needs and the psychosocial characteristics of patients with PAH, are non-existent. But it is known that the persons affected by rare diseases are more vulnerable, on the psychological, social, economic and cultural planIn all the stages of the treatment, patients with PAH are confronted with heavy psychosocial situations, in a context of vital risk, with exceptional medicinal treatments (intravenous administration at home).

• QoL might be differently affected by these changes according to situational and dispositional psychological dimensions.
• the predictive role of these characteristics on the current and later quality of life, as well as the impact of diverse cognitive mediators and strategies to cope with the disease, should be investigated.The respiratory diseases department of the Montpellier hospital is regional competence center for PAH in Languedoc-Roussillon, under the aegis of the national reference center (the respiratory diseases department of Antoine Béclère hospital, Le Petit-Clamart).