Time - Related Cuff Pressure and Volume of the Laryngeal Tube With the Use of Nitrous Oxide
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Purpose
The purpose of this study is to investigate the time-related intracuff pressure and volume change (which reflects the pharyngeal pressure) of the LT during anesthesia with N2O.
| Condition | Intervention |
|---|---|
|
Adult Disease |
Device: laryngeal tube (VBM Medizintechnik) |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Prospective |
| Official Title: | Time - Related Cuff Pressure and Volume of the Laryngeal Tube With the Use of Nitrous Oxide |
- intracuff pressure [ Time Frame: 1-4 hours ] [ Designated as safety issue: Yes ]measured intracuff pressure of LT with N2O during intraoperative period
| Enrollment: | 75 |
| Study Start Date: | May 2008 |
| Study Completion Date: | December 2009 |
| Primary Completion Date: | December 2009 (Final data collection date for primary outcome measure) |
| Groups/Cohorts | Assigned Interventions |
|---|---|
|
intracuff pressure N2O
measured intracuff pressure of LT with N2o during operative period
|
Device: laryngeal tube (VBM Medizintechnik)
laryngeal tube number 4
Other Name: The laryngeal tube (VBM Medizintechnik, Sulz, Germany)
|
Detailed Description:
Background : The laryngeal tube airway (LT) is an extraglottic airway device with a proximal and distal conical cuff designed to secure a patient's airway during either spontaneous breathing or controlled ventilation. Application of this device with the use of N2O may be related to the ischemic change of the oropharyngeal mucosa. The objective of this study was to investigate the time-related intracuff pressure and volume change (which reflects the pharyngeal pressure) of the LT during anesthesia with N2O.
Methods : Seventy-five patients were studied with the use of LT size 4. N2O (66%) and isoflurane were used to maintain anesthesia. Initial intracuff pressure and volume were recorded for airway sealing during ventilation. Time-course changes of the intracuff pressure followed by recording every 10 min. If the intracuff pressure reached 100 cmH2O, the cuff was deflated to the initial intracuff pressure and the volume of deflated air and postoperative airway complications were recorded.
Eligibility| Ages Eligible for Study: | 15 Years to 75 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
patients with general anesthesia
Inclusion Criteria:
- American Society of Anesthesiologist physical status I or II
- Undergoing elective orthopedic surgery and surgery of breast under general anesthesia with an expected duration of 60 min or more
Exclusion Criteria:
- Height was < 155 or >180 cm (for the use of laryngeal tube size 4)
- Body mass index ≥35 kg/m2
- Preexisting laryngotracheal disease
- Risk of pulmonary aspiration of gastric contents.
Contacts and Locations More Information
No publications provided
| Responsible Party: | Assistant Professor Nalinee Kovitwanawong, Department of Anesthesiology Faculty of Medicine Prince of Songkla University Thailand |
| ClinicalTrials.gov Identifier: | NCT01346384 History of Changes |
| Other Study ID Numbers: | LT-N2O |
| Study First Received: | April 25, 2011 |
| Last Updated: | May 3, 2011 |
| Health Authority: | Thailand: Ethical Committee |
Keywords provided by Prince of Songkla University:
|
intracuff pressure laryngeal tube nitrous oxide |
Additional relevant MeSH terms:
|
Nitrous Oxide Analgesics, Non-Narcotic Analgesics Sensory System Agents Peripheral Nervous System Agents Physiological Effects of Drugs Pharmacologic Actions |
Central Nervous System Agents Therapeutic Uses Anesthetics, Inhalation Anesthetics, General Anesthetics Central Nervous System Depressants |
ClinicalTrials.gov processed this record on May 19, 2013