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Finding Early Rheumatoid Arthritis

The recruitment status of this study is unknown because the information has not been verified recently.
Verified May 2012 by Brigham and Women's Hospital.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by (Responsible Party):
Matthew H. Liang, MD, Brigham and Women's Hospital
ClinicalTrials.gov Identifier:
NCT01341314
First received: April 22, 2011
Last updated: May 23, 2012
Last verified: May 2012
  Purpose

Research has shown that early aggressive use of medicines may stop rheumatoid arthritis (RA)or slow its damage. The key to this is to find people with early symptoms which could be RA and have them get a diagnosis, treatment and follow-up.

This study will recruit persons who've gone to the internet looking for information about their symptoms. After answering a screening survey, the person with possible symptoms will be linked to the study website for a more detailed symptom questionnaire.

After completing that questionnaire the person will receive information about the second part of the study which includes an examination with a rheumatologist (arthritis doctor)and laboratory tests.

Based on the joint examination and laboratory tests, the rheumatologist will tell the person the likelihood of having RA, and make recommendations and if needed a referral for care and treatment. Treatment is not a part of this study.

This study will also compare the information on the subject's questionnaires to the doctor's joint examination and the laboratory tests with the hope of developing a simple inexpensive case finding questionnaire.


Condition
Joint Pain
Stiffness

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Proof of Concept of an Internet-based Series Design Case-finding System for Very Early Rheumatoid Arthritis.

Resource links provided by NLM:


Further study details as provided by Brigham and Women's Hospital:

Biospecimen Retention:   Samples Without DNA

Frozen serum for future assay development


Estimated Enrollment: 200
Study Start Date: January 2010
Estimated Study Completion Date: July 2013
Estimated Primary Completion Date: January 2013 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

persons with joint pain or swelling for less than 3 months

Criteria

Inclusion Criteria:

  • Joint pain or swelling for less than 3 months
  • Be able to use the internet

Exclusion Criteria:

  • Non English speaking
  • Diagnosis of rheumatoid arthritis
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01341314

Locations
United States, Massachusetts
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Sponsors and Collaborators
Brigham and Women's Hospital
  More Information

No publications provided

Responsible Party: Matthew H. Liang, MD, Principal Investigator, Brigham and Women's Hospital
ClinicalTrials.gov Identifier: NCT01341314     History of Changes
Other Study ID Numbers: ArthFndtn
Study First Received: April 22, 2011
Last Updated: May 23, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by Brigham and Women's Hospital:
joint pain
stiffness

Additional relevant MeSH terms:
Arthralgia
Arthritis, Rheumatoid
Arthritis
Autoimmune Diseases
Connective Tissue Diseases
Immune System Diseases
Joint Diseases
Musculoskeletal Diseases
Pain
Rheumatic Diseases
Signs and Symptoms

ClinicalTrials.gov processed this record on November 27, 2014