Relationship Between Gestational Diabetes and Type 2 Diabetes (GDM)
The overall objective of this research project is to study preventive practices among women with prior GDM and their impact on the T2D-related risk profile.
Type 2 Diabetes
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Key Determinants of Type 2 Diabetes Prevention Among Women With a History of Gestational Diabetes Mellitus|
- Glucose tolerance assessed using a 75g-Oral Glucose Tolerance Test (OGTT) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
- overweight/obesity [ Time Frame: 1 year ] [ Designated as safety issue: No ]
- abdominal obesity [ Time Frame: 1 year ] [ Designated as safety issue: No ]
- inflammatory state [ Time Frame: 1 year ] [ Designated as safety issue: No ]
- metabolic syndrome [ Time Frame: 1 year ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
whole blood; serum; white cell.
|Study Start Date:||September 2009|
|Estimated Study Completion Date:||December 2014|
|Primary Completion Date:||September 2012 (Final data collection date for primary outcome measure)|
Type 2 diabetes (T2D) is a growing public health problem owing to its prevalence as well as its high morbidity and mortality rates. The identification of high-risk populations is of great importance particularly because the onset of T2D can be prevented or delayed by lifestyle modifications. Among high-risk populations, women with previously diagnosed gestational diabetes mellitus (GDM) are at particularly high risk of developing T2D. The success in reducing the occurrence of T2D among women with previous GDM could be achieved only if appropriate preventive measures are undertaken. According to the American Diabetes Association (ADA) and the Canadian Diabetes Association (CDA), lifestyle modifications aimed at reducing body weight and increasing physical activity are recommended and women are encouraged to be breastfeeding their infants. Certain factors have been suggested as determinants of behavioral practices in women with prior GDM including cognitive and environmental factors. A better understanding of these issues is essential for developing effective preventive strategies and possibly reducing the prevalence of T2D in the population.The overall objective of this research project is to study preventive practices among women with prior GDM and their impact on the T2D-related risk profile.
|Laval University, Institute of Nutraceuticals and Functional Foods|
|Quebec, Canada, G1V 0A6|
|Principal Investigator:||Julie Robitaille, R.D., Ph.D.||Laval University|