Trial record 17 of 25 for:
Open Studies | "Hyponatremia"
Frequency and Origin of Dysnatremias in the Emergency Department
This study is not yet open for participant recruitment.
Verified April 2012 by University Hospital Inselspital, Berne
Sponsor:
University Hospital Inselspital, Berne
Collaborator:
Steering committee of the NCCR
Information provided by:
University Hospital Inselspital, Berne
ClinicalTrials.gov Identifier:
NCT01326429
First received: March 29, 2011
Last updated: April 17, 2012
Last verified: April 2012
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Purpose
Hypo- and hypernatremia are the most frequent electrolyte disorders found in hospitalized patients. The increasing use of diuretics and other medications influencing the water and sodium homeostasis potentially lead to a rise in the prevalence of the electrolyte disorders. Only little data is available on the frequency and the mechanisms leading to hypo-/hypernatremia.
Thus, the investigators aim to A.) determine the frequency of hypo- and hypernatremia in the emergency department of a large tertiary university hospital and B.) explore the mechanisms leading to the development of dysnatremias by detailed clinical and laboratory examinations.
| Condition |
|---|
|
Hyponatremia Hypernatremia |
| Study Type: | Observational |
| Study Design: | Observational Model: Case-Only Time Perspective: Prospective |
| Official Title: | Frequency and Origin of Dysnatremias in the Emergency Department |
Further study details as provided by University Hospital Inselspital, Berne:
Primary Outcome Measures:
- Frequency of hypo- and hypernatremia in the emergency department [ Time Frame: approx. 6 months ] [ Designated as safety issue: No ]We aim to determine the frequency of hypo- and hypernatremia in the emergency department of a large tertiary university hospital.
Secondary Outcome Measures:
- Origin of hypo- and hypernatremia in the emergency department [ Time Frame: approx. 6 months ] [ Designated as safety issue: No ]We try to investiagte the mechanisms leading to the development of hypo- and hypernatremia in patients admitted to the emergency department.
Biospecimen Retention: Samples With DNA
whole blood
| Estimated Enrollment: | 200 |
| Study Start Date: | August 2012 |
| Groups/Cohorts |
|---|
|
Hypernatremia
Patients admitted to the emergency department with a serum sodium exceeding 145 mmol/L.
|
|
Hyponatremia
Patients admitted to the emergency room with a serum sodium below 135 mmol/L.
|
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Study Population
All patients admitted to the emergency department of a large tertiary university hospital with a serum sodium below 135 mmol/L (hyponatremia) or exceeding 145 mmol/L.
Criteria
Inclusion Criteria:
- Serum sodium below 135 mmol/L (i.e. hyponatremia); serum sodium exceeding 145 mmol/L (hypernatremia)
Exclusion Criteria:
- Patients below age 18 years; patients declining study participation.
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01326429
Contacts
| Contact: Gregor Lindner, M.D. | +41326329629 | gregor.lindner@insel.ch |
| Contact: Felix J Frey, M.D. | +41316329629 | felix.frey@insel.ch |
Locations
| Switzerland | |
| Inselspital Bern, University of Bern | Not yet recruiting |
| Bern, Switzerland, 3010 | |
| Contact: Gregor Lindner, M.D. +41316329629 gregor.lindner@insel.ch | |
| Contact: Felix J Frey, M.D. +41316329629 felix.frey@insel.ch | |
| Principal Investigator: Gregor Lindner, M.D. | |
| Sub-Investigator: Daniel Ackermann, M.D. | |
Sponsors and Collaborators
University Hospital Inselspital, Berne
Steering committee of the NCCR
Investigators
| Principal Investigator: | Gregor Lindner, M.D. | Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern |
| Study Chair: | Felix J Frey, M.D. | Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern |
More Information
Additional Information:
No publications provided
| Responsible Party: | Gregor Lindner M.D., Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern |
| ClinicalTrials.gov Identifier: | NCT01326429 History of Changes |
| Other Study ID Numbers: | KEK 019/11 |
| Study First Received: | March 29, 2011 |
| Last Updated: | April 17, 2012 |
| Health Authority: | Switzerland: Ethikkommission |
Keywords provided by University Hospital Inselspital, Berne:
|
Sodium Hyponatremia Hypernatremia Emergency department |
Additional relevant MeSH terms:
|
Emergencies Hypernatremia Hyponatremia Disease Attributes |
Pathologic Processes Water-Electrolyte Imbalance Metabolic Diseases |
ClinicalTrials.gov processed this record on May 16, 2013