Determinants of Penumbra in Acute Ischemic Stroke Patients

This study is currently recruiting participants. (see Contacts and Locations)
Verified May 2014 by Rambam Health Care Campus
Sponsor:
Information provided by (Responsible Party):
rambam62, Rambam Health Care Campus
ClinicalTrials.gov Identifier:
NCT01323413
First received: March 24, 2011
Last updated: May 1, 2014
Last verified: May 2014
  Purpose

The purpose of the study is to examine the influence of demographic, clinical and laboratory characteristics on the presence and size of penumbra in acute ischemic stroke patients and to determine those of them which related significantly and independently to the presence and size of Penumbra. The examined factors will include demographic variables such as age, gender, ethnic background, vascular risk factors and medical history, clinical parameters such as time from stroke onset until arrival to the hospital, results of neurological evaluation by NIHSS and imaging findings, laboratory tests such as body temperature, blood pressure, glucose level, renal functions etc. and imaging findings - the presence and the size of collateral blood vessels, the state of carotid arteries (by CTA). The possible correlation between all this parameters and the presence and the size of penumbra as detected by CTP will be further examined.


Condition
Acute Ischemic Stroke

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Determinants of Penumbra in Acute Ischemic Stroke Patients

Resource links provided by NLM:


Further study details as provided by Rambam Health Care Campus:

Estimated Enrollment: 250
Study Start Date: April 2011
Estimated Study Completion Date: December 2016
Estimated Primary Completion Date: November 2016 (Final data collection date for primary outcome measure)
Groups/Cohorts
stroke
acute ischemic stroke patients

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

neurological ward

Criteria

Inclusion Criteria:

  • Acute ischemic stroke patients hospitalized in Rambam Health Care Campus between 2008-2010, and which have underwent neurological evaluation including NIHSS scale, Brain CT, CT angio and Ct perfusion.

Exclusion Criteria:

  • Intracranial hemorrhage of any other brain condition
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01323413

Contacts
Contact: Gregory J Telman, MD +972-48542161 g_telman@rambam.health.gov.il

Locations
Israel
Rambam Health Care Campus Recruiting
Haifa, Israel
Contact: Ahmad Khalaila, MD    =972-502061686      
Sub-Investigator: Ahmad Khalaila, MD         
Sponsors and Collaborators
Rambam Health Care Campus
  More Information

No publications provided

Responsible Party: rambam62, MD, Rambam Health Care Campus
ClinicalTrials.gov Identifier: NCT01323413     History of Changes
Other Study ID Numbers: 0080-11CTIL
Study First Received: March 24, 2011
Last Updated: May 1, 2014
Health Authority: Israel: Ministry of Health

Keywords provided by Rambam Health Care Campus:
stroke
penumbra
determinants
CT perfusion

Additional relevant MeSH terms:
Ischemia
Stroke
Cerebral Infarction
Pathologic Processes
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases
Brain Infarction
Brain Ischemia

ClinicalTrials.gov processed this record on August 19, 2014