Systemic Inflammation Versus Acute Pain in Total Knee Arthroplasty (TKA)
In this study we evaluate if there is a correlation between acute pain and systemic inflammatory markers after total Knee Arthroplasty (TKA).
Other Acute Postoperative Pain
Systemic Inflammatory Response Syndrome
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||The Relation Between Systemic Inflammatory Markers and Acute Pain in TKA|
- Systemic inflammation vs. pain [ Time Frame: 1 week ] [ Designated as safety issue: No ]The correlation between pain and systemic inflammatory markers (CRP and IL6)
Biospecimen Retention: Samples With DNA
Blood samples for C reactive protein and interleukin 6 analysis.
|Study Start Date:||August 2009|
|Study Completion Date:||October 2011|
|Primary Completion Date:||October 2011 (Final data collection date for primary outcome measure)|
Total knee arthroplasty
Patients operated with elective, unilateral total knee arthroplasty.
The correlation between acute pain and systemic inflammatory markers after total Knee Arthroplasty (TKA) is evaluated.
Level of systemic inflammatory markers (CRP and IL6) are measured preoperatively and 4 and 24 hours postoperatively. These measurements are correlated to postoperative pain (a detailed assessment of pain at rest and during ambulation).
We pole blood-samples collected prospectively (from two data set)