Distinction of Cone Outer Segment Tips by Spectral-Domain Optical Coherence Tomography in Normal Eyes
The aim of this study is to investigate the incidence and possible causes of obscured or disrupted cone outer segment tips line at fovea in spectral-domain optical coherence tomography images of normal eyes.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Distinction of Cone Outer Segment Tips by Spectral-Domain Optical Coherence Tomography in Normal Eyes|
- Microstructural analysis by Spectral domain optical coherence tomography [ Time Frame: one year ] [ Designated as safety issue: No ]SD-OCT images of 6 mm scans were taken using Cirrus HD-OCT (OCT 4000, Carl Zeiss Meditec, Dublin, CA) with 5 line raster (5LR) and high-definition 5 line raster (HD5LR) modes.
- Visual acuity [ Time Frame: one year ] [ Designated as safety issue: No ]Each subject had a routine eye examination including measuring best-corrected visual acuity (BCVA) and intraocular pressure.
|Study Start Date:||March 2010|
|Study Completion Date:||March 2011|
|Primary Completion Date:||March 2011 (Final data collection date for primary outcome measure)|
Thirty-seven eyes of 37 individuals without eye diseases
Other: Optical coherence tomography
Optical coherence tomography
Other Name: Cirrus HD-OCT (Carl Zeiss Meditec)
Thirty-seven eyes of 37 individuals without eye diseases were included in this study. Optical Coherence Tomography (OCT) images were taken using Cirrus HD-OCT (Carl Zeiss Meditec) with 5 line raster and high-definition 5 line raster modes. Images with signal strength weaker than 5/10 were excluded. Distinction of COST line and the integrity of COST line, external limiting membrane, and the photoreceptor inner segment and outer segment junction at the fovea were recorded. Demographic data, refractive error of the eyes, signal strengths of the OCT images were acquired for analysis.