Effect of Remote Ischemic Preconditioning on Children Undergoing Cardiac Surgery
This study is conducted in order to evaluate the effect of remote ischemic preconditioning on children undergoing cardiac surgery, especially focusing on possible differences according to preoperative cyanosis.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Prevention
|Official Title:||Effect of Remote Ischemic Preconditioning on Children Undergoing Cardiac Surgery: Implication of Preoperative Cyanosis|
- troponin level [ Time Frame: within the 1 day after operation ] [ Designated as safety issue: Yes ]troponin level will be checked 1, 6, 12 and 24 hours after operation. Ater making a graph (troponin-time), area under the curve will bw calculated.
|Study Start Date:||October 2009|
|Study Completion Date:||December 2011|
|Primary Completion Date:||July 2011 (Final data collection date for primary outcome measure)|
|Experimental: remote ischemic preconditioning||
Other: RIPC (remote ischemic preconditioning)
RIPC will be performed by four 5-min cycles of lower limb ischemia and 5 in reperfusion using blood-pressure cuff inflated to a pressure 15 mmHg greater than the systolic arterial pressure measured via arterial line.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01311310
|Korea, Republic of|
|Seoul national university hospital|
|Seoul, Korea, Republic of|
|Seoul National University Hospital|
|Seoul, Korea, Republic of, 110-744|