Circadian Rhythm of Blood Lactate

This study has been completed.
Sponsor:
Collaborator:
State University of New York - Downstate Medical Center
Information provided by (Responsible Party):
Axel Schlitt, Martin-Luther-Universität Halle-Wittenberg
ClinicalTrials.gov Identifier:
NCT01303848
First received: February 24, 2011
Last updated: May 1, 2012
Last verified: May 2012
  Purpose

To elucidate whether blood lactate, lipid transfer proteins and PPARs/CLOCK/Bal1 have a circadian rhythm


Condition Intervention
Healthy
Other: Blood Sampling

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Circadian Rhythm of Blood Lactate, Lipid Transferproteins and Genetic Markers (PPARs, CLOCK, Bmal1)

Resource links provided by NLM:


Further study details as provided by Martin-Luther-Universität Halle-Wittenberg:

Primary Outcome Measures:
  • Circadian rhythm of blood lactate [ Time Frame: 5 months ] [ Designated as safety issue: No ]
    Blood samples


Secondary Outcome Measures:
  • Circadian rhythm of Lipid transfer proteins [ Time Frame: 5 months ] [ Designated as safety issue: No ]
    Blood

  • Circadian rhythm of PPARs, CLOCK and Bal1 [ Time Frame: 5 months ] [ Designated as safety issue: No ]
    Blood


Enrollment: 30
Study Start Date: February 2011
Study Completion Date: May 2012
Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Healthy probands
Healthy probands, age between 18 and 40 years
Other: Blood Sampling
Blood Sampling over 24 hours

Detailed Description:

Blood will be drawn fasting and then every hour over a period of 24 hours in 30 healthy probands.

  Eligibility

Ages Eligible for Study:   18 Years to 40 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

30 healthy probands

Criteria

Inclusion Criteria:

  • Age between 18 and 40 years old

Exclusion Criteria:

  • Inability/unwilling to give written informed consent
  • Chronic disease
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01303848

Locations
Germany
University Clinic Halle, Martin Luther-University Halle-Wittenberg
Halle (Saale), Germany, 06120
Sponsors and Collaborators
Martin-Luther-Universität Halle-Wittenberg
State University of New York - Downstate Medical Center
Investigators
Principal Investigator: Axel Schlitt, MD Department of Medicine III, University Clinic Halle, Martin Luther-University Halle-Wittenberg
  More Information

No publications provided

Responsible Party: Axel Schlitt, PD Dr. med. habil., Martin-Luther-Universität Halle-Wittenberg
ClinicalTrials.gov Identifier: NCT01303848     History of Changes
Other Study ID Numbers: UKH2011Sport1
Study First Received: February 24, 2011
Last Updated: May 1, 2012
Health Authority: Germany: Federal Institute for Drugs and Medical Devices

Keywords provided by Martin-Luther-Universität Halle-Wittenberg:
Blood lactate
Lipid transfer proteins
Lactate
PLTP
CETP
PPARs
CLOCk
Bal1

ClinicalTrials.gov processed this record on July 31, 2014