Aqueous Humor Dynamics and Biometric Parameters in Eyes of Children
This study is not yet open for participant recruitment.
Verified June 2012 by University of Nebraska
Information provided by (Responsible Party):
University of Nebraska
First received: February 3, 2011
Last updated: June 13, 2012
Last verified: June 2012
The purpose of this study is to determine the effect of age and ethnic background on ocular aqueous humor dynamics and biometric parameters. Data of normal healthy children and adults will be used as controls for future study of juvenile glaucoma, and diabetes and potentially for any other condition that affects intraocular pressure in children.
||Observational Model: Cohort
||Aqueous Humor Dynamics and Biometric Parameters in Eyes of Children
| Estimated Enrollment:
| Study Start Date:
| Estimated Study Completion Date:
| Estimated Primary Completion Date:
||April 2014 (Final data collection date for primary outcome measure)
Children of Caucasian descent
Healthy children of Caucasian descent.
Adults of Caucasian descent
Healthy adult eyes of Caucasian descent.
Children of African-American descent
Healthy children of African-American descent.
Adults of African-American descent
Healthy adults of African-American descent.
|Ages Eligible for Study:
||15 Years to 50 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
- Caucasian or African American
- Subjects must not have any ocular diseases
- Children, 15 - 18 years of age
- Adults, 30 - 50 years of age
- Women who are pregnant or lactating
- Aphakia or pseudophakia
- Chronic or recurrent severe ocular inflammatory disease.
- Ocular infection or inflammation within three (3) months of screening visit.
- History of clinically significant or progressive retinal disease such as retinal degeneration, diabetic retinopathy or retinal detachment.
- Any abnormality preventing reliable tonometry of either eye.
- History of any ocular pathology (including dry eye).
- A cup-to-disc ratio greater than 0.8
- History of intraocular surgery
- History of ocular laser surgery
- History of hypersensitivity or allergy to beta blockers and sulfa drugs.
- History of severe, unstable or uncontrolled cardiovascular, hepatic or renal disease.
- History of bronchial asthma or chronic obstructive pulmonary disease (COPD).
- Inability to discontinue contact lens wear.
- Diagnosis of ocular hypertension or glaucoma or any ocular disease
Please refer to this study by its ClinicalTrials.gov identifier: NCT01290588
|University of Nebraska Medical Center, Department of Ophthalmology and Visual Sciences
|Omaha, Nebraska, United States, 68198-5540 |
|Contact: Carol Toris, PhD 402-559-9472 firstname.lastname@example.org |
|Contact: Donna Neely, MBA 402-559-5706 email@example.com |
University of Nebraska
||Carol Toris, PhD
||University of Nebraska Medical Center, Department of Ophthalmology and Visual Sciences
No publications provided
ClinicalTrials.gov processed this record on March 06, 2014
||University of Nebraska
History of Changes
|Other Study ID Numbers:
|Study First Received:
||February 3, 2011
||June 13, 2012
||United States: Institutional Review Board