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Lung Ultrasound for Acute Dyspnea in Emergency Department

This study has been completed.
Sponsor:
Collaborators:
Cancer Epidemiology Unit-AOU San Giovanni Battista, Turin, Italy
San Luigi Gonzaga Hospital
Emergency Medicine & Surgery Unit-Pinerolo General Hospital, ASL TO 3, Italy
Emergency Medicine and Surgery Unit -AO Mauriziano, Turin, Italy
Emergency Medicine & Surgery Unit-Martini Hospital, ASL TO 1, Turin, Italy
Emergency Medicine & Surgery Unit-Cardinal Massaia Hospital, ASL AT, Asti, Italy
Emergency Medicine Unit-AOU San Luigi Gonzaga, Orbassano, Italy
Emergency Medicine Department-AO Santa Croce e Carle, Cuneo, Italy
Information provided by:
University of Turin, Italy
ClinicalTrials.gov Identifier:
NCT01287429
First received: January 28, 2011
Last updated: November 19, 2012
Last verified: October 2010
History of Changes
  Purpose

Dyspnea is a frequent symptom in patients admitted to the Emergency Department (ED); discriminating between cardiogenic and non-cardiogenic dyspnea is a common clinical dilemma. The initial diagnostic work-out is often not very accurate in defining the etiology and the underlying pathophysiology. In the last years, lung ultrasound (US) has emerged as a useful real-time bedside diagnostic tool in the critical patient. The aim of this study was to evaluate the accuracy, reproducibility, and diagnostic impact of pleural and lung US, performed by emergency physicians at the time of patient first presentation to the ED, in identifying cardiac causes of acute dyspnea.


Condition Intervention
Dyspnea
Congestive Heart Failure
 Other: lung and pleural ultrasound

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Lung Ultrasound for Acute Dyspnea in Emergency Department - Prospective Multicenter Study on Accuracy, Reproducibility, and Diagnostic Impact of Lung Ultrasound in the Evaluation of Patients With Dyspnea in the Emergency Department

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University of Turin, Italy:

Enrollment: 1005
Study Start Date: October 2010
Study Completion Date: October 2012
Primary Completion Date: October 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
acute dyspnea Other: lung and pleural ultrasound
After the initial diagnostic work-out (medical history, physical examination, EKG, arterious blood gas), the emergency physician will classify dyspnoea in cardiogenic or respiratory dyspnoea and write it down in a specific form (clinical form). Immediately after this, lung and pleural ultrasound will be performed: the physician will describe it and evaluate the etiology again (integrated evaluation form). Then a chest X-ray evaluation will be performed for each patient.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Hospital Emergency Departments sample

Criteria

Inclusion Criteria:

  • Patients had to present to the ED with a principal complaint of shortness of breath, defined as either the sudden onset of dyspnea with no history of chronic dyspnea or an increase in the severity of chronic dyspnea in the last 48 hours;
  • Presence of an emergency physician with lung US experience at the time of enrollment;
  • US examination within 30 minutes after the start of the clinical evaluation.

Exclusion Criteria:

  • Dyspnea cases clearly due to neither cardiogenic nor respiratory etiology will considered not eligible.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01287429

Locations
Italy
Emergency Medicine & Surgery Unit - Cardinal Massaia Hospital
Asti, Italy, 14100
Emergency Department - AO Santa Croce e Carle
Cuneo, Italy
Emergency Medicine Unit - AOU San Luigi Gonzaga
Orbassano, Italy, 10043
Emergency Medicine & Surgery Unit - Pinerolo General Hospital, ASL TO 3
Pinerolo, Italy, 10064
Emergency Medicine and Surgery Unit- AO Mauriziano
Turin, Italy, 10128
Emergency Medicine & Surgery Unit - Martini Hospital, ASL TO 2
Turin, Italy, 10141
Emergency Department - AOU San Giovanni Battista
Turin, Italy, 10126
Sponsors and Collaborators
University of Turin, Italy
Cancer Epidemiology Unit-AOU San Giovanni Battista, Turin, Italy
San Luigi Gonzaga Hospital
Emergency Medicine & Surgery Unit-Pinerolo General Hospital, ASL TO 3, Italy
Emergency Medicine and Surgery Unit -AO Mauriziano, Turin, Italy
Emergency Medicine & Surgery Unit-Martini Hospital, ASL TO 1, Turin, Italy
Emergency Medicine & Surgery Unit-Cardinal Massaia Hospital, ASL AT, Asti, Italy
Emergency Medicine Unit-AOU San Luigi Gonzaga, Orbassano, Italy
Emergency Medicine Department-AO Santa Croce e Carle, Cuneo, Italy
Investigators
Principal Investigator: Emanuele Pivetta Cancer Epidemiology Unit - University of Turin
  More Information

Publications:

Responsible Party: Emanuele Pivetta, Cancer Epidemiology Unit - University of Turin
ClinicalTrials.gov Identifier: NCT01287429     History of Changes
Other Study ID Numbers: CEU-UTurin-001
Study First Received: January 28, 2011
Last Updated: November 19, 2012
Health Authority: Italy: Ethics Committee

Keywords provided by University of Turin, Italy:
Ultrasonography

Additional relevant MeSH terms:
Dyspnea
Emergencies
Heart Failure
Respiration Disorders
Respiratory Tract Diseases
Signs and Symptoms, Respiratory
 Signs and Symptoms
Disease Attributes
Pathologic Processes
Heart Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on May 22, 2013