Orthoptic Changes Following Photorefractive Keratectomy
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Purpose
Purpose: To detect orthoptic changes in patients undergoing photorefractive keratectomy (PRK). Method: This interventional case series was performed on 297 eyes of 150 patients who were candidates for PRK. Complete ophthalmic evaluations focusing on orthoptic examinations were performed before and 3 months after PRK. Results: Before PRK, two (1.3%) patients had esotropia that remained unchanged postoperatively. However, 3 (2%) patients had distance exotropia preoperatively which improved after PRK. Of 12 cases (8%) with preoperative exotropia at near, 3 (2%) cases became orthophoric. Six patients (4%) developed postoperative near exotropia. A significant reduction in means of convergence and divergence amplitudes (P<0.001) and a meaningful increase in mean of near point of convergence (NPC) (P<0.006) were noticed after PRK. A reduction of ≥10 PD in convergence amplitude and ≥5 PD in divergence amplitude were detected in 10 and 5 patients, respectively. Four patients had an preoperative NPC>10 cm which was not changed by the surgery. Out of 9 (6%) patients with baseline stereopsis >60 seconds of arc, 2 (1.33%) cases showed an improvement in stereopsis following PRK. None of the patients complained of postoperative diplopia. Conclusion: Eye deviation in patients undergoing PRK may improve or remain unchanged after operation and postoperative deviations can develop following this surgery. Diminishing of fusional amplitude and increasing of NPC as well as improving of stereopsis may also happen after PRK. Therefore, a preoperative orthoptic examination in patients with any concerning histories and/or motility issues on routine exam is recommended before performing PRK.
| Condition | Intervention | Phase |
|---|---|---|
|
Orthoptic Changes |
Procedure: Kerato refractive Surgery |
Phase 3 |
| Study Type: | Interventional |
| Study Design: | Allocation: Non-Randomized Intervention Model: Single Group Assignment Primary Purpose: Supportive Care |
| Official Title: | Orthoptic Changes Following Photorefractive Keratectomy |
- orthoptic changes [ Time Frame: before and after KRS ] [ Designated as safety issue: No ]Prism / (deviation)
- VA , Streopsis , deviation , fusion , NPC [ Time Frame: before and after KRS ]Snellen , Titmus, prism, ruler
| Study Start Date: | April 2008 |
| Study Completion Date: | April 2009 |
| Primary Completion Date: | January 2009 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
| Experimental: Kerato refractive Surgery |
Procedure: Kerato refractive Surgery
This interventional case series was performed on 297 eyes of 150 patients who were candidates for PRK. Complete ophthalmic evaluations focusing on orthoptic examinations were performed before and 3 months after PRK.
|
Eligibility| Ages Eligible for Study: | 18 Years to 59 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
>18 yrs / refractive errors / with consent
Exclusion Criteria:
< 18 / corneal opacity - keratoconus
Dry eye / diabetes / collages vacuolar disease
Contacts and Locations| Iran, Islamic Republic of | |
| Labbafinejad medical center | |
| Tehran, Iran, Islamic Republic of | |
| Principal Investigator: | zhaleh rajavi, Assistant Professor | Imam Hossein Medical Center |
More Information
No publications provided
| Responsible Party: | Zhale Rajavi, Ophthalmic Research center |
| ClinicalTrials.gov Identifier: | NCT01279993 History of Changes |
| Other Study ID Numbers: | 8659 |
| Study First Received: | January 19, 2011 |
| Last Updated: | January 19, 2011 |
| Health Authority: | Iran: Ethics Committee |
ClinicalTrials.gov processed this record on May 19, 2013