Red Wine and Ageing and Atherosclerosis
Recruitment status was Recruiting
The investigators will evaluate 100 regular red wine consumer men and 100 abstainers men from 50 years-old to 70 years-old by coronary risk prevalence, mood status, anthropometric measures, daily caloric ingest, lipid profile, carotid intimal media thickness, brachial flow mediate dilatation, coronary tomographic angiography and leucocyte telomere length.
The sample size has been calculated expecting that regular red wine ingestion would lead to a five year old younger vascular ageing indexes measured by carotid intimal media thickness, coronary artery calcium scores and leucocyte telomere length longer than those abstainers subjects at same age.
The investigators hypothesized that regular wine consumers present less coronary lesion and coronary calcium score on coronary tomographic angiography, lower carotid intimal media thickness and higher mean telomere length due the benefice of wine.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||The Red Wine Project: a Study of Ageing Indexes and Prevalence of Atherosclerosis in Regular Red Wine Consumers Versus Abstainers|
total blood sample
|Study Start Date:||October 2009|
|Estimated Study Completion Date:||April 2011|
|Estimated Primary Completion Date:||March 2011 (Final data collection date for primary outcome measure)|
red wine usual consumer versus abstemious
|Heart Insitute ( InCor) University of Sao Paulo||Recruiting|
|Sao Paulo, Brazil, 05403-000|
|Contact: Protasio L Da Luz, mD, PhD 55 11 3069 5952 ext - firstname.lastname@example.org|
|Principal Investigator:||Protasio L Da Luz, MD, PhD||University of Sao Paulo|