After Eighty Study
The rationale of the present clinical trial is to study whether an invasive strategy in clinical stable patients over 80 years with NSTEMI/UAP may improve rates of death, reinfarction, stroke, need of urgent revascularisation, myocardial function and quality of life. The invasive approach involves coronary angiography with immediate evaluation for three different treatment options; 1. Percutaneous coronary intervention (PCI), 2. Coronary artery bypass graft (CABG) or 3. medical treatment. Clinical practice shows that older patients are commonly treated less vigorously than younger patients and the present guidelines are based on a considerably younger population.
Coronary Heart Disease
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||A Randomised Prospective Study of an Invasive Strategy Versus Medical Therapy in Patients Over 80 Years With Non ST-Elevation Myocardial Infarction (NSTEMI) or Unstable Angina Pectoris (UAP)|
- Composite endpoints. [ Time Frame: One year follow up. ] [ Designated as safety issue: No ]Does an invasive strategy in clinical stable patients over 80 years with NSTEMI/UAP improve rates of death, reinfarction, stroke and need of urgent revascularisation?
- Death of any cause [ Time Frame: One year from randomization ] [ Designated as safety issue: No ]
|Study Start Date:||September 2010|
|Contact: Bjørn Bendz, MD PhD (chairman)||+47-95802582||Bjorn.Bendz@oslo-universitetssykehus.no|
|Contact: Nicolai K. Tegn, PhD email@example.com|
|Oslo University Hospital, Rikshospitalet||Recruiting|
|Contact: Bjørn Bendz, PhD +4795802582 Bjorn.Bendz@oslo-universitetssykehus.no|
|Contact: Nicolai K. Tegn, PhD student +4798696554 firstname.lastname@example.org|