The Effects of Vibration on Hypoxia

This study has been completed.
Sponsor:
Information provided by:
Institute of Aviation Medicine, Oslo, Norway
ClinicalTrials.gov Identifier:
NCT01245491
First received: November 19, 2010
Last updated: January 13, 2011
Last verified: January 2011
  Purpose

The purpose of this study is:

  1. To study the effect of whole-body vibration on partial pressure of oxygen in arterial blood (PaO2), under hypobaric hypoxic conditions.
  2. To study the effects of whole-body vibration and hypobaric hypoxia on visual contrast sensitivity.
  3. To se if there is an increase in cytokines and other biomarkers under different hypobaric hypoxic conditions Our main hypothesis is that whole-body vibration may cause PaO2 to drop to a lower level, at a given altitude; than would be the case if there were no vibration present.

Condition Intervention
Hypoxia
Other: Vibration

Study Type: Interventional
Study Design: Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Primary Purpose: Basic Science
Official Title: The Effects of Vibration on Hypoxia

Further study details as provided by Institute of Aviation Medicine, Oslo, Norway:

Primary Outcome Measures:
  • PaO2 [ Time Frame: 14 minutes ] [ Designated as safety issue: Yes ]
    Assessed at six different altitudes

  • PaO2 [ Time Frame: 35 minutes ] [ Designated as safety issue: Yes ]
    Assessed at six dfferent altitudes


Secondary Outcome Measures:
  • Ventilation [ Time Frame: 14 minutes ] [ Designated as safety issue: No ]
    Assessed at six different altitudes, over a period of three minutes.

  • Ventilation [ Time Frame: 35 minutes ] [ Designated as safety issue: No ]
    Assessed over a periode of three minutes, at six different altitudes.


Enrollment: 13
Study Start Date: October 2010
Study Completion Date: December 2010
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Intervention Details:
    Other: Vibration
    Whole-body vibration, 17 Hz, 1.1ms-2
  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

Exclusion Criteria:

  • Stay at altitude over 2000 m last two weeks prior to study-start.
  • Severe head injury
  • Cardiovascular disease
  • lung disease
  • Decompression sickness
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01245491

Sponsors and Collaborators
Institute of Aviation Medicine, Oslo, Norway
Investigators
Principal Investigator: Tor A Hansen, Msc. Institute of Aviation Medicine
  More Information

No publications provided

Responsible Party: Anthony S. Wagstaff, Institute of Aviation Medicine
ClinicalTrials.gov Identifier: NCT01245491     History of Changes
Other Study ID Numbers: REK-2010/2021b
Study First Received: November 19, 2010
Last Updated: January 13, 2011
Health Authority: Norway: Regional Ethics Commitee

ClinicalTrials.gov processed this record on September 16, 2014