Pain and Schizophrenia

The recruitment status of this study is unknown because the information has not been verified recently.
Verified November 2010 by University Hospital, Strasbourg, France.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier:
NCT01244542
First received: November 17, 2010
Last updated: August 24, 2011
Last verified: November 2010
  Purpose

The aim of the investigators project is to explore the mechanisms of pain insensitivity in patients with schizophrenia, in order to prevent its invalidating consequences. The investigators will couple methods of experimental psychology with EEG and blood samplings, in order to distinguish the role of non-painful perception, attention, aversive effects, and pain expression, and the investigators will explore an original neurobiological hypothesis regarding the activation of opioid receptors.


Condition
Pain
Schizophrenia

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Pain and Schizophrenia

Resource links provided by NLM:


Further study details as provided by University Hospital, Strasbourg, France:

Estimated Enrollment: 100
Study Start Date: August 2011
Estimated Study Completion Date: January 2014
Estimated Primary Completion Date: January 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts
1-
Patients with schizophrenia
2-
Healthy controls (controls matched with patients on age, sex and education level)

  Eligibility

Ages Eligible for Study:   18 Years to 55 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
  • Primary care and day clinic in Strasbourg, Erstein and Besançon
  • Healthy controls from or near Strasbourg, Erstein or Besançon.
Criteria

Inclusion Criteria:

  • Patients with schizophrenia (criteria DSM IV) or healthy controls matched with patients on age, sex and education level
  • 18-55 years old

Exclusion Criteria:

  • Past history affecting CNS
  • Intake of psychotropic drugs, except for patients
  • Metabolic disorder affecting sensory processing (diabetes)
  • Intake of benzodiazepines
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01244542

Contacts
Contact: Anne GIERSCH, MD 03 88 11 64 71 giersch@alsace.u-strasbg.fr

Locations
France
Service de Psychiatrie Adulte2, Place Saint-Jacques - ZA 481, Centre Hospitalier Saint-Jacques Not yet recruiting
Besançon Cedex, France, 25030
Contact: Pierre VANDEL, MD, PhD    33 3 81 21 86 11    pierre.vandel@univ-fcomte.fr   
Principal Investigator: Pierre VANDEL, MD, PhD         
Sub-Investigator: Emmanuel HAFFEN, MD, PhD         
Service de Psychiatrie Adulte, Secteur G11, Centre Hospitalier de Erstein, 13 route de Krafft Not yet recruiting
Erstein Cedex, France, 67152
Contact: Jea n-Philippe LANG    33 3 90 64 21 16    jp.lang@ch-erstein.fr   
Contact: Jea n-Philippe LANG, MD    33 3 90 64 21 16    jp.lang@ch-erstein.fr   
Centre d'évaluation et de traitement de la douleur, HôpitalCivil, Hôpitaux Universitaires de Strasbourg, 1, place de l'Hôpital Recruiting
Strasbourg Cedex, France, 67 091
Contact: Eric SALVAT, MD    33 3 88 11 64 83    eric.salvat@chru-strasbourg.fr   
Principal Investigator: Eric SALVAT, MD         
Sub-Investigator: André MULLER, MD, PhD         
Centre d'Investigation Clinique (UF 1043), Nouvel Hôpital Civil, 1, place de l'hôpital Not yet recruiting
STRASBOURG Cedex, France, 67091
Contact: Catherine MUTTER, MD    33 3 69 55 06 18    catherine.mutter@chru-strasbourg.fr   
Contact: Catherine MUTTERBRANDT, MD    33 3 69 55 06 18    catherine.mutter@chru-strasbourg.fr   
Sponsors and Collaborators
University Hospital, Strasbourg, France
Investigators
Study Director: Anne Giersch, MD University Hospital, Strasbourg, France
  More Information

No publications provided

Responsible Party: Christine GEILLER, directeur de la Direction de la Recherche Clinique et des Innovations, University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier: NCT01244542     History of Changes
Other Study ID Numbers: 4706
Study First Received: November 17, 2010
Last Updated: August 24, 2011
Health Authority: France: Ministry of Health

Keywords provided by University Hospital, Strasbourg, France:
Schizophrenia
DSM IV criteria
Pain insensitivity
Painful perception
Opioid receptors

Additional relevant MeSH terms:
Schizophrenia
Schizophrenia and Disorders with Psychotic Features
Mental Disorders

ClinicalTrials.gov processed this record on July 23, 2014