Smoking Cessation Program in the Preadmission Clinic: The Use of a Teachable Moment
This study has been completed.
Information provided by (Responsible Party):
Dr. Frances Chung, University Health Network, Toronto
First received: November 16, 2010
Last updated: December 17, 2013
Last verified: November 2013
The Objective of this study is to introduce a practically feasible multifaceted intervention in the preadmission clinic to help reduce smoking in preoperative surgical patients. The investigators aim to study the effectiveness of such a program in promoting positive change in smoking behavior among patients before surgery. The forced abstinence enforced on patients during hospital stay for their surgery can also be used to help smokers remain tobacco free long term. A significant percentage of surgical patients will be receptive to smoking cessation interventions in the preadmission clinic and will refrain from smoking at 24 and 52 weeks after starting the treatment.
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Supportive Care
Primary Outcome Measures:
- A significant percentage of surgical patients will be receptive to smoking cessation interventions in the preadmission clinic and will refrain from smoking at 24 and 52 weeks after starting the treatment. [ Time Frame: 2 years ] [ Designated as safety issue: No ]
Secondary Outcome Measures:
- Patients who receive interventions but do not quit smoking will have reduced number of cigarettes consumed /day or improved "stage of change" (determined by Prochaska and DiClemente's Model) at 24 and 52 weeks after starting the treatment. [ Time Frame: 2 years ] [ Designated as safety issue: No ]
| Study Start Date:
| Study Completion Date:
| Primary Completion Date:
||November 2010 (Final data collection date for primary outcome measure)
Placebo Comparator: Placebo
patient will receive placebo pills
Days 1 - 3: 0.5 mg once daily (1 table each day) Days 4 - 7: 0.5 mg twice daily (1 in the morning and 1 in the evening) Days 8 - 12 weeks 1.0 mg twice daily (1 in the morning and 1 in the evening)
|Ages Eligible for Study:
||18 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
- The investigators will recruit patients who are assessed in preadmission clinic and scheduled for elective surgical procedures within the next 8 to 30 days.
- Patients should be 18 yrs of age, have smoked an average 10 cigarettes/day or more during the previous year and had no period of smoking abstinence longer than 3 months in the past year.
- current pregnancy, breastfeeding;
- major depression, panic disorder, psychosis, or bipolar disorder within the prior year;
- use of nicotine replacement or bupropion within the previous 3 months;
- cardiovascular disease within the past 6 months;
- a serious or unstable disease within the past 6 months;
- drug or alcohol abuse or dependence within the past year;
- and use of tobacco products other than cigarettes or marijuana use within the previous month;
- participating in any other studies
- Patients who cannot understand English or have any form of cognitive impairment will be excluded.
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01243203
|University Health Network, Department of Anesthesai
|Toronto, Ontario, Canada, M5T2S8 |
University Health Network, Toronto
No publications provided
||Dr. Frances Chung, Staff Anesthesiologist, University Health Network, Toronto
History of Changes
|Other Study ID Numbers:
|Study First Received:
||November 16, 2010
||December 17, 2013
||Canada: Health Canada
Keywords provided by University Health Network, Toronto:
Smoking, surgery, Anesthesia, quit
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on August 28, 2014
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs