Does Valproate Increase Levels of Folate Receptor Autoantibodies in Women?
Women who take folate (folic acid) before getting pregnant can lower the risk of giving birth to infant with certain birth defects. However, some medications may affect the action of folate. The purpose of this study is to compare the effect of two anti-epileptic drugs on how folate works in our body.
|Study Design:||Observational Model: Case Control
Time Perspective: Cross-Sectional
|Official Title:||Does Valproate Increase Levels of Folate Receptor Autoantibodies in Women?|
- To examine association between levels of folate receptor autoantibodies and therapy (VPA, LTG) in women [ Time Frame: n/a (cross-sectional study) ] [ Designated as safety issue: No ]
|Study Start Date:||October 2010|
|Primary Completion Date:||April 2013 (Final data collection date for primary outcome measure)|
|United States, New York|
|North Shore Long Island Jewish Health System|
|Great Neck, New York, United States, 11021|
|Principal Investigator:||Cynthia Harden, MD||North Shore-Long Island Jewish Medical Center|